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Targeted Approaches to T-Cell Lymphoma

Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia
Monash Health, Melbourne, VIC 3168, Australia
Epworth Healthcare, Melbourne, VIC 3002, Australia
Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, VIC 3000, Australia
Author to whom correspondence should be addressed.
Academic Editor: Stephen Opat
J. Pers. Med. 2021, 11(6), 481;
Received: 12 May 2021 / Revised: 24 May 2021 / Accepted: 25 May 2021 / Published: 27 May 2021
(This article belongs to the Special Issue Targeted Treatment of Lymphoma, Leukaemia and Myeloma)
The T-cell lymphomas are a rare group of Non-Hodgkin’s lymphomas derived from mature T-lymphocytes. They are divided broadly into the Peripheral T-cell lymphomas and the Cutaneous T-cell lymphomas. Clinical outcomes vary widely but are generally unsatisfactory with current treatments. The development of an understanding of the various critical pathways in T-cell lymphogenesis and subsequent identification of therapeutic targets has led to a rapid expansion of the previously underwhelming T-cell lymphoma armament. This review aims to provide an up-to-date overview of the current state of targeted therapies in the T-cell lymphomas, including novel antibody-based treatments, small molecule inhibitors and immune-based therapies. View Full-Text
Keywords: novel agents; monoclonal antibodies; immunotherapy novel agents; monoclonal antibodies; immunotherapy
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MDPI and ACS Style

Harrop, S.; Abeyakoon, C.; Van Der Weyden, C.; Prince, H.M. Targeted Approaches to T-Cell Lymphoma. J. Pers. Med. 2021, 11, 481.

AMA Style

Harrop S, Abeyakoon C, Van Der Weyden C, Prince HM. Targeted Approaches to T-Cell Lymphoma. Journal of Personalized Medicine. 2021; 11(6):481.

Chicago/Turabian Style

Harrop, Sean, Chathuri Abeyakoon, Carrie Van Der Weyden, and H. M. Prince 2021. "Targeted Approaches to T-Cell Lymphoma" Journal of Personalized Medicine 11, no. 6: 481.

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