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Review

Targeted Approaches to T-Cell Lymphoma

1
Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia
2
Monash Health, Melbourne, VIC 3168, Australia
3
Epworth Healthcare, Melbourne, VIC 3002, Australia
4
Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, VIC 3000, Australia
*
Author to whom correspondence should be addressed.
Academic Editor: Stephen Opat
J. Pers. Med. 2021, 11(6), 481; https://doi.org/10.3390/jpm11060481
Received: 12 May 2021 / Revised: 24 May 2021 / Accepted: 25 May 2021 / Published: 27 May 2021
(This article belongs to the Special Issue Targeted Treatment of Lymphoma, Leukaemia and Myeloma)
The T-cell lymphomas are a rare group of Non-Hodgkin’s lymphomas derived from mature T-lymphocytes. They are divided broadly into the Peripheral T-cell lymphomas and the Cutaneous T-cell lymphomas. Clinical outcomes vary widely but are generally unsatisfactory with current treatments. The development of an understanding of the various critical pathways in T-cell lymphogenesis and subsequent identification of therapeutic targets has led to a rapid expansion of the previously underwhelming T-cell lymphoma armament. This review aims to provide an up-to-date overview of the current state of targeted therapies in the T-cell lymphomas, including novel antibody-based treatments, small molecule inhibitors and immune-based therapies. View Full-Text
Keywords: novel agents; monoclonal antibodies; immunotherapy novel agents; monoclonal antibodies; immunotherapy
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MDPI and ACS Style

Harrop, S.; Abeyakoon, C.; Van Der Weyden, C.; Prince, H.M. Targeted Approaches to T-Cell Lymphoma. J. Pers. Med. 2021, 11, 481. https://doi.org/10.3390/jpm11060481

AMA Style

Harrop S, Abeyakoon C, Van Der Weyden C, Prince HM. Targeted Approaches to T-Cell Lymphoma. Journal of Personalized Medicine. 2021; 11(6):481. https://doi.org/10.3390/jpm11060481

Chicago/Turabian Style

Harrop, Sean, Chathuri Abeyakoon, Carrie Van Der Weyden, and H. M. Prince 2021. "Targeted Approaches to T-Cell Lymphoma" Journal of Personalized Medicine 11, no. 6: 481. https://doi.org/10.3390/jpm11060481

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