Relationship between the Corticospinal and Corticocerebellar Tracts and Their Role in Upper Extremity Motor Recovery in Stroke Patients
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Participants
2.2. MRI Data Acquisition
2.3. DTI Data Processing for Extraction of CST and CCT FA Values
2.4. Statistical Analysis
3. Results
4. Discussion
4.1. The Corticospinal Tract Injury Associated with Motor Recovery
4.2. The Corticocerebellar Tract Injury Associated with Motor Recovery
4.3. The Relationship between the Corticospinal and Corticocerebellar Tracts for Motor Recovery
4.4. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Characteristics | n = 70 |
---|---|
Age (years) | |
Mean ± SD | 59.1 ± 12.9 |
Sex (n) | |
Male | 42 |
Female | 28 |
Lesion side (n) | |
Right | 34 |
Left | 36 |
Lesion location (n) | |
Supratentorial | 57 |
Infratentorial | 13 |
Lesion volume (cm3) | |
Mean ± SD | 49.9 ± 78.1 |
Initial impairment, mean ± SD | |
FMA-UE | 13.8 ± 9.4 |
NIHSS | 8.9 ± 4.4 |
MMSE | 23.0 ± 9.1 |
Model | Estimate | t | p | R2 | Adjusted R2 |
---|---|---|---|---|---|
CST*CCT | 0.358 | 0.329 | |||
Intercept | 281.42 | 2.12 | 0.038 | ||
CST | −340.6 | −2.19 | 0.032 | ||
CCT | −313.5 | −2.44 | 0.018 | ||
CST*CCT | 397.9 | 2.63 | 0.011 |
Tracts | Proportional CST FA > 0.9 (n = 26) | Proportional CST FA ≤ 0.9 (n = 44) | ||||
---|---|---|---|---|---|---|
t | p | R2 | t | p | R2 | |
CST | −0.89 | 0.382 | 0.032 | 4.75 | <0.001 | 0.349 * |
CCT | 2.63 | 0.015 | 0.223 * | −1.16 | 0.252 | 0.031 |
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Lee, J.; Chang, W.H.; Kim, Y.-H. Relationship between the Corticospinal and Corticocerebellar Tracts and Their Role in Upper Extremity Motor Recovery in Stroke Patients. J. Pers. Med. 2021, 11, 1162. https://doi.org/10.3390/jpm11111162
Lee J, Chang WH, Kim Y-H. Relationship between the Corticospinal and Corticocerebellar Tracts and Their Role in Upper Extremity Motor Recovery in Stroke Patients. Journal of Personalized Medicine. 2021; 11(11):1162. https://doi.org/10.3390/jpm11111162
Chicago/Turabian StyleLee, Jungsoo, Won Hyuk Chang, and Yun-Hee Kim. 2021. "Relationship between the Corticospinal and Corticocerebellar Tracts and Their Role in Upper Extremity Motor Recovery in Stroke Patients" Journal of Personalized Medicine 11, no. 11: 1162. https://doi.org/10.3390/jpm11111162