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Diagnostics 2014, 4(2), 57-93;

Endoscopic Optical Coherence Tomography for Clinical Gastroenterology

Department of Electrical Engineering and Computer Science and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
Veterans Affairs Boston Healthcare System and Harvard Medical School, Boston, MA 02115, USA
Author to whom correspondence should be addressed.
Received: 2 February 2014 / Revised: 18 April 2014 / Accepted: 22 April 2014 / Published: 5 May 2014
(This article belongs to the Collection Hybrid Imaging in Medicine)
Full-Text   |   PDF [1004 KB, uploaded 5 May 2014]   |  


Optical coherence tomography (OCT) is a real-time optical imaging technique that is similar in principle to ultrasonography, but employs light instead of sound waves and allows depth-resolved images with near-microscopic resolution. Endoscopic OCT allows the evaluation of broad-field and subsurface areas and can be used ancillary to standard endoscopy, narrow band imaging, chromoendoscopy, magnification endoscopy, and confocal endomicroscopy. This review article will provide an overview of the clinical utility of endoscopic OCT in the gastrointestinal tract and of recent achievements using state-of-the-art endoscopic 3D-OCT imaging systems. View Full-Text
Keywords: optical coherence tomography; optical biopsy; endoscopic imaging; Barrett’s esophagus; inflammatory bowel disease optical coherence tomography; optical biopsy; endoscopic imaging; Barrett’s esophagus; inflammatory bowel disease

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This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Tsai, T.-H.; Fujimoto, J.G.; Mashimo, H. Endoscopic Optical Coherence Tomography for Clinical Gastroenterology. Diagnostics 2014, 4, 57-93.

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