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Article

A Hybrid Model for Ultrasound Image-Based Breast Cancer Diagnosis Using EfficientNet-V2 and Vision Transformer

by
Zainab Qahtan Mohammed
1,*,
Amel Tuama Alhussainy
2,
Ihsan Salman Jasim
1 and
Asraf Mohamed Moubark
3,*
1
Department of Computer Science, College of Basic Education, Diyala University, Diyala 32001, Iraq
2
Department of Artificial Intelligence Engineering Techniques, Technical Engineering College of Computer and AI/Kirkuk, Northern Technical University, Kirkuk 36001, Iraq
3
Department of Electrical, Electronic and Systems Engineering, Faculty of Engineering and Built Environment, University of Kebangsaan Malaysia, Bangi Selangor 43600, Malaysia
*
Authors to whom correspondence should be addressed.
Diagnostics 2026, 16(8), 1176; https://doi.org/10.3390/diagnostics16081176
Submission received: 1 March 2026 / Revised: 30 March 2026 / Accepted: 9 April 2026 / Published: 15 April 2026
(This article belongs to the Special Issue The Role of AI in Ultrasound, 2nd Edition)

Abstract

Background/Objectives: Breast cancer continues to be one of the most serious and common afflictions affecting women around the globe. Despite ultrasound imaging being an effective method for the detection of abnormalities in dense breast tissues, there are a number of drawbacks when utilizing this method, including the subjective nature of the imaging and the variant nature of the imaging due to the cognitive biases of the interpreting expert and the experience of the interpreting expert. The above factors are the cause of the increased need in the implementation of AI-driven models for diagnostic analysis. In this research, we provide a hybrid deep learning-based framework for cancer classification of the breast cancer ultrasound image dataset (‘BUSI dataset’). Methods: The contributing models of the proposed architecture involve the combination of a light ViT encoder and an EfficientNetV2-RW-S feature extractor. The combination mentioned leverage the positive sensitivities of the convolutional neural networks (CNNs) and the global reasoning neural networks (i.e., transformers) in the explanation of the architecture. The reason being, EfficientNetV2 diminishes the capture of the fine-grained morphological components of the lesions, edges, and echogenic variances of the tissue, whereas the transformer model diminishes the long-range dependencies of the lesions and other surrounding tissues. Results: The experimental results from the proposed hybrid model of the architecture demonstrates an enhanced classification accuracy of 97.95%, in contrast to the self-standing models of the architecture, the hybrid model supersedes the isolated ViT model (i.e., 89%) and the isolated CNN model (i.e., 80%) frameworks. Furthermore, the proposed model hybrid architecture also diminishes the overall self-attention computational complexity of the proposed model by substantially diminishing the number of tokens reaching an overall count of 10 (from the vast 197 tokens). This further leads to a substantial decrease in the memory and cost expended during the attention processes. Conclusion: Overall, this study proposes a method for the improved diagnostic and computational analysis, suggesting the proposed architecture to be a potential framework for use in the contemporary clinical environments.
Keywords: breast cancer; ultrasound; Efficient Net; vision transformer; hybrid model; classification breast cancer; ultrasound; Efficient Net; vision transformer; hybrid model; classification

Share and Cite

MDPI and ACS Style

Qahtan Mohammed, Z.; Tuama Alhussainy, A.; Salman Jasim, I.; Mohamed Moubark, A. A Hybrid Model for Ultrasound Image-Based Breast Cancer Diagnosis Using EfficientNet-V2 and Vision Transformer. Diagnostics 2026, 16, 1176. https://doi.org/10.3390/diagnostics16081176

AMA Style

Qahtan Mohammed Z, Tuama Alhussainy A, Salman Jasim I, Mohamed Moubark A. A Hybrid Model for Ultrasound Image-Based Breast Cancer Diagnosis Using EfficientNet-V2 and Vision Transformer. Diagnostics. 2026; 16(8):1176. https://doi.org/10.3390/diagnostics16081176

Chicago/Turabian Style

Qahtan Mohammed, Zainab, Amel Tuama Alhussainy, Ihsan Salman Jasim, and Asraf Mohamed Moubark. 2026. "A Hybrid Model for Ultrasound Image-Based Breast Cancer Diagnosis Using EfficientNet-V2 and Vision Transformer" Diagnostics 16, no. 8: 1176. https://doi.org/10.3390/diagnostics16081176

APA Style

Qahtan Mohammed, Z., Tuama Alhussainy, A., Salman Jasim, I., & Mohamed Moubark, A. (2026). A Hybrid Model for Ultrasound Image-Based Breast Cancer Diagnosis Using EfficientNet-V2 and Vision Transformer. Diagnostics, 16(8), 1176. https://doi.org/10.3390/diagnostics16081176

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