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Unveiling Hidden Abscesses: The Clinical Utility of Diffusion-Weighted Whole-Body Imaging with Background Suppression (DWIBS) in Metastatic Abscess Screening

1
Department of Rehabilitation Medicine, Fukui General Hospital, Fukui 910-8561, Japan
2
Department of Internal Medicine, Fukui General Hospital, Fukui 910-8561, Japan
3
Graduate School of Health Science, Fukui Health Science University, Fukui 910-3190, Japan
4
Department of Orthopedics, Fukui General Hospital, Fukui 910-8561, Japan
5
Department of Radiology, Fukui General Hospital, Fukui 910-8561, Japan
6
Department of Infectious Diseases, Faculty of Medical Sciences, University of Fukui, Fukui 910-1193, Japan
*
Author to whom correspondence should be addressed.
Diagnostics 2026, 16(2), 223; https://doi.org/10.3390/diagnostics16020223
Submission received: 10 December 2025 / Revised: 5 January 2026 / Accepted: 9 January 2026 / Published: 10 January 2026
(This article belongs to the Special Issue Advances in Inflammation and Infection Imaging: 2nd Edition)

Abstract

A 74-year-old man with type 2 diabetes presented with fever, urinary retention, and urinary difficulties. Initial abdominal Computed Tomography (CT) suggested acute pyelonephritis, but a low-density area in the prostate was overlooked. Following the confirmation of methicillin-resistant Staphylococcus aureus (MRSA) in blood and urine cultures, comprehensive screening for metastatic abscesses was necessitated. Diffusion-weighted whole-body imaging with background suppression (DWIBS) was utilized and clearly identified a prostatic abscess (PA), nephritis, urethritis, and subcutaneous cysts. These findings also raised suspicion of pyogenic vertebral osteomyelitis. Crucially, the PA, urethritis, subcutaneous cysts, and potentially the vertebral osteomyelitis were either overlooked or not detected by initial CT imaging. DWIBS allows for simultaneous whole-body screening and serves as a useful adjunctive tool for identifying minute abscesses, which may assist in detecting inflammatory foci that are sometimes overlooked by conventional imaging. Unlike CT, DWIBS avoids radiation and contrast agents, and is significantly more cost-effective than positron emission tomography-CT (PET-CT). DWIBS can thus serve as a useful, non-invasive tool for the early detection and exclusion of abscesses in other organs when metastatic abscess formation is suspected or cultures are positive for microorganisms causing metastatic abscesses.
Keywords: abscess; metastatic lesion; prostate abscess; diffusion-weighted whole-body imaging with background suppression; MRI; methicillin-resistant Staphylococcus aureus; diagnosis; radiology abscess; metastatic lesion; prostate abscess; diffusion-weighted whole-body imaging with background suppression; MRI; methicillin-resistant Staphylococcus aureus; diagnosis; radiology

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MDPI and ACS Style

Hayashi, K.; Hayashi, M.; Izumi, R.; Sato, M.; Hayashi, S.; Iwasaki, T.; Sakamaki, I.; Kobayashi, Y. Unveiling Hidden Abscesses: The Clinical Utility of Diffusion-Weighted Whole-Body Imaging with Background Suppression (DWIBS) in Metastatic Abscess Screening. Diagnostics 2026, 16, 223. https://doi.org/10.3390/diagnostics16020223

AMA Style

Hayashi K, Hayashi M, Izumi R, Sato M, Hayashi S, Iwasaki T, Sakamaki I, Kobayashi Y. Unveiling Hidden Abscesses: The Clinical Utility of Diffusion-Weighted Whole-Body Imaging with Background Suppression (DWIBS) in Metastatic Abscess Screening. Diagnostics. 2026; 16(2):223. https://doi.org/10.3390/diagnostics16020223

Chicago/Turabian Style

Hayashi, Koji, Maho Hayashi, Rina Izumi, Mamiko Sato, Seigaku Hayashi, Toshiko Iwasaki, Ippei Sakamaki, and Yasutaka Kobayashi. 2026. "Unveiling Hidden Abscesses: The Clinical Utility of Diffusion-Weighted Whole-Body Imaging with Background Suppression (DWIBS) in Metastatic Abscess Screening" Diagnostics 16, no. 2: 223. https://doi.org/10.3390/diagnostics16020223

APA Style

Hayashi, K., Hayashi, M., Izumi, R., Sato, M., Hayashi, S., Iwasaki, T., Sakamaki, I., & Kobayashi, Y. (2026). Unveiling Hidden Abscesses: The Clinical Utility of Diffusion-Weighted Whole-Body Imaging with Background Suppression (DWIBS) in Metastatic Abscess Screening. Diagnostics, 16(2), 223. https://doi.org/10.3390/diagnostics16020223

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