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Diagnostics
Volume 15
Issue 4
10.3390/diagnostics15040506
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Article
Peer-Review Record

Pitfalls in Ultrasound Diagnosis of Vascular Malformations: A Retrospective Review of 14 Nonvascular Tumors Treated as Vascular Malformations

Diagnostics 2025, 15(4), 506; https://doi.org/10.3390/diagnostics15040506
by Shintaro Mitamura 1,2, Kosuke Ishikawa 1,2,*, Yuki Sasaki 1,2, Naoki Murao 2 and Satoru Sasaki 2
Reviewer 1:
Sang Yub Lee
Reviewer 2:
Dimitrij Kuhelj
Diagnostics 2025, 15(4), 506; https://doi.org/10.3390/diagnostics15040506
Submission received: 21 January 2025 / Revised: 12 February 2025 / Accepted: 18 February 2025 / Published: 19 February 2025
(This article belongs to the Special Issue Ultrasound in the Diagnosis and Management of Skin Diseases)

Round 1

Reviewer 1 Report

Comments and Suggestions for Authors

General comment

This study provides a comprehensive retrospective analysis of cases where nonvascular tumors were initially misdiagnosed as vascular malformations. The findings are clinically significant and contribute to improving the accuracy of ultrasound diagnosis. The manuscript is well-structured, and the imaging descriptions are informative.

 

Specific comment

In Table 2, please discuss differences between "high-flow" in arteriovenous malformation and "hypervascular" in angiomyoma.

Do you have specific differential points or parameters during Doppler ultrasound?

This differential diagnosis will be the key point of this manuscript. Please discuss this point more in detail.

Comments on the Quality of English Language

Grammar and Style: Some sentences are lengthy and could be simplified for better readability.

Author Response

Please see the attachment.

Author Response File: Author Response.pdf

Reviewer 2 Report

Comments and Suggestions for Authors

Clinical presentation of disease in Introduction should be included.

Classification should be only mentioned, not described in extenso.

Role of CT and DSA should be described in Introduction, since many patients from the cohort had this two types of investigations.

In clinical features potential changes in skin colour should be included.

 

Case 1: no VM present without Gd enhancement

Case 4- why was sclerotherapy used in suspected high- flow malformsation?

 

Changes in skin colour are not included in presentations of different VM in Discussion.

 

Conclusions should be based on study findings- evaluation of the treatment should be performed after each therapy and in a case of failure alternative pathology should be suspected.

 

 

Author Response

Please see the attachment.

Author Response File: Author Response.pdf

Round 2

Reviewer 2 Report

Comments and Suggestions for Authors

Thank you for revision.

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