Interpreting Discordant Monosomy 3 FISH and Chromosomal Microarray Analysis Results in Uveal Melanoma
Abstract
1. Materials and Methods
2. Figure and Table Legends
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Patient #1 | Patient #2 | |
---|---|---|
Mutations | No clinically significant variance detected. | No clinically significant variance detected. |
Chromosomal Gains | 2.27 Mb gain in 9q33.1 encompassing 6 genes (ASTN2, SNORA70C, LOC101928797, TLR4, LINC02578, BRINP1). | Gain of chromosomes 7, 8, 18, 19, and 22. |
Chromosomal Losses | No chromosomal losses detected. | Monosomy 3 at limit of detection with additional losses of chromosomes 4, 12, and 16q. |
Monosomy 3 FISH Status | Positive, 63.5% of 200 cells counted (28% cutoff). | Negative. |
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Long, C.P.; Coley, N.; Thorson, J.; Lin, J.H. Interpreting Discordant Monosomy 3 FISH and Chromosomal Microarray Analysis Results in Uveal Melanoma. Diagnostics 2023, 13, 946. https://doi.org/10.3390/diagnostics13050946
Long CP, Coley N, Thorson J, Lin JH. Interpreting Discordant Monosomy 3 FISH and Chromosomal Microarray Analysis Results in Uveal Melanoma. Diagnostics. 2023; 13(5):946. https://doi.org/10.3390/diagnostics13050946
Chicago/Turabian StyleLong, Christopher P., Nicholas Coley, John Thorson, and Jonathan H. Lin. 2023. "Interpreting Discordant Monosomy 3 FISH and Chromosomal Microarray Analysis Results in Uveal Melanoma" Diagnostics 13, no. 5: 946. https://doi.org/10.3390/diagnostics13050946
APA StyleLong, C. P., Coley, N., Thorson, J., & Lin, J. H. (2023). Interpreting Discordant Monosomy 3 FISH and Chromosomal Microarray Analysis Results in Uveal Melanoma. Diagnostics, 13(5), 946. https://doi.org/10.3390/diagnostics13050946