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Volume 13
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10.3390/diagnostics13050926
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Article

The Characteristics of Sentinel Lymph Node Biopsy in Cutaneous Melanoma and the Particularities for Elderly Patients—Experience of a Single Clinic

by
Florin Bobircă
1,2,3,
Tiberiu Tebeică
3,
Adela Pumnea
4,
Dan Dumitrescu
1,2,3,*,
Cristina Alexandru
5,*,
Laura Banciu
3,
Ionela Loredana Popa
1,6,
Anca Bobircă
5,7,†,
Mihaela Leventer
3,† and
Traian Pătrașcu
1,2,†
1
Surgery Department, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania
2
Surgery Department, Dr. Ion Cantacuzino Clinical Hospital, 011437 Bucharest, Romania
3
Dr. Leventer Centre, 011216 Bucharest, Romania
4
Gauss Clinics, 011255 Bucharest, Romania
5
Internal Medicine and Rheumatology Department, Dr. Ion Cantacuzino Clinical Hospital, 011437 Bucharest, Romania
6
Marie Curie Emergency Children’s Hospital, 041451 Bucharest, Romania
7
Internal Medicine and Rheumatology Department, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania
*
Authors to whom correspondence should be addressed.
†
These authors contributed equally to this work.
Diagnostics 2023, 13(5), 926; https://doi.org/10.3390/diagnostics13050926
Submission received: 15 February 2023 / Revised: 26 February 2023 / Accepted: 27 February 2023 / Published: 1 March 2023
(This article belongs to the Special Issue Diagnosis and Radiotherapy in Oncology)
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Abstract

Background: Melanoma is a malignant tumor that determines approximately 80% of deaths as skin cancer-related. The sentinel lymph node (SLN) represents the first filter of tumor cells toward systemic dissemination. The primary objective was to outline the surgical specifics of the sentinel lymph node biopsy (SLNB) technique, correlate the location of the lymph node with the radiotracer load, and identify the characteristics of older patients. Methods: In this prospective study, 122 cases of malignant melanoma needing SLNB technique were included, between June 2019 and November 2022, resulting in 162 lymph nodes removed. Results: Patients’ mean age was 54.3 ± 14.4 years old, the prevalence of 70 years and older being 20.5%. The rate of positive SLN was 24.6%, with a single drainage in 68.9% of cases. The frequency of seroma was 14.8%, while reintervention 1.6%. The inguinal nodes had the highest preoperative radiotracer load (p = 0.015). Patients 70 years old or older had significantly more advanced-stage melanoma (68.0% vs. 45.4%, p = 0.044, OR = 2.56) and a higher rate of positive SLN (40.0% vs. 20.6%, p = 0.045,OR = 2.57). Melanoma of the head and neck was more common among older individuals (32.0% vs. 9.3%, p = 0.007,OR = 4.60). Conclusions: The SLNB has a low rate of surgical complications and the positivity of SLN is not related to radiotracer load. Elderly patients are at risk for head and neck melanoma, have more advanced stages, a higher SLN positivity, and a greater rate of surgical complications.
Keywords: melanoma; sentinel lymph node biopsy; elderly melanoma; sentinel lymph node biopsy; elderly

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MDPI and ACS Style

Bobircă, F.; Tebeică, T.; Pumnea, A.; Dumitrescu, D.; Alexandru, C.; Banciu, L.; Popa, I.L.; Bobircă, A.; Leventer, M.; Pătrașcu, T. The Characteristics of Sentinel Lymph Node Biopsy in Cutaneous Melanoma and the Particularities for Elderly Patients—Experience of a Single Clinic. Diagnostics 2023, 13, 926. https://doi.org/10.3390/diagnostics13050926

AMA Style

Bobircă F, Tebeică T, Pumnea A, Dumitrescu D, Alexandru C, Banciu L, Popa IL, Bobircă A, Leventer M, Pătrașcu T. The Characteristics of Sentinel Lymph Node Biopsy in Cutaneous Melanoma and the Particularities for Elderly Patients—Experience of a Single Clinic. Diagnostics. 2023; 13(5):926. https://doi.org/10.3390/diagnostics13050926

Chicago/Turabian Style

Bobircă, Florin, Tiberiu Tebeică, Adela Pumnea, Dan Dumitrescu, Cristina Alexandru, Laura Banciu, Ionela Loredana Popa, Anca Bobircă, Mihaela Leventer, and Traian Pătrașcu. 2023. "The Characteristics of Sentinel Lymph Node Biopsy in Cutaneous Melanoma and the Particularities for Elderly Patients—Experience of a Single Clinic" Diagnostics 13, no. 5: 926. https://doi.org/10.3390/diagnostics13050926

APA Style

Bobircă, F., Tebeică, T., Pumnea, A., Dumitrescu, D., Alexandru, C., Banciu, L., Popa, I. L., Bobircă, A., Leventer, M., & Pătrașcu, T. (2023). The Characteristics of Sentinel Lymph Node Biopsy in Cutaneous Melanoma and the Particularities for Elderly Patients—Experience of a Single Clinic. Diagnostics, 13(5), 926. https://doi.org/10.3390/diagnostics13050926

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