Placenta, the Key Witness of COVID-19 Infection in Premature Births
Abstract
:1. Introduction
2. Materials and Methods
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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MATERNAL CHARACTERISTICS | COVID-19 PATIENTS (%) | NON-COVID-19 PATIENTS (%) | p-Value | ||
---|---|---|---|---|---|
material age (years-percentage) | 18–30 y.o. | 41 | 18–30 y.o. | 53.8 | 0.164 |
31–40 y.o. | 46.2 | 31–40 y.o. | 41 | ||
41–45 y.o. | 12.8 | 41–45 y.o. | 5.1 | ||
BMI (percentage) | <18.5 | 7.7 | <18.5 | 7.7 | 0.749 |
18.5–24.9 | 69.2 | 18.5–24.9 | 69.2 | ||
25–30 | 12.8 | 25–30 | 17.9 | ||
>30 | 10.3 | >30 | 5.1 | ||
gesta (number-percentage) | 1 | 33.3 | 1 | 43.6 | 0.581 |
2 | 23.1 | 2 | 17.9 | ||
≥3 | 43.6 | ≥3 | 38.5 | ||
para (number-percentage) | 1 | 51.3 | 1 | 59 | 0.696 |
2 | 28.2 | 2 | 28.2 | ||
≥3 | 20.5 | ≥3 | 12.8 | ||
monitored pregnancy (percentage) | Yes | 69.2 | Yes | 41 | 0.012 |
No | 30.8 | No | 59 | ||
gestational age of distribution (weeks-percentage) | <28 w | 7.7 | <28 w | 17.9 | 0.112 |
28–31 w | 12.8 | 28–31 w | 17.9 | ||
32–36 w | 79.5 | 32–36 w | 64.1 | ||
premature rupture of membranes (percentage) | YES | 23.1 | YES | 51.3 | 0.010 |
No | 76.9 | No | 48.7 | ||
birth type (vaginal vs. caesarean-percentage) | Vaginal birth | 23.1 | Vaginal birth | 94.9 | <0.001 |
Caesarean birth | 76.9 | Caesarean birth | 5.1 |
p-Value | |||
---|---|---|---|
symptomatic (percentage) | Yes | 53.8 | 0.000 |
No | 46.2 | ||
oxygen therapy (percentage) | Yes | 23.1 | 0.002 |
No | 76.9 | ||
intubation (percentage) | Yes | 17.9 | 0.006 |
No | 82.1 | ||
associated pathologies (percentage) | Yes | 30.8 | 0.001 |
No | 69.2 | ||
apgar scores (percentage) | <5 | 10.3 | 0.000 |
5–8 | 61.6 | ||
9 | 23.1 | ||
10 | 5.1 |
COVID-19 PATIENTS | NON-COVID-19 PATIENTS | p-Value | |
---|---|---|---|
placental infarct (percentage) | 64.1 | 30.8 | 0.003 |
perivillous fibrin deposits (percentage) | 59 | 46.2 | 0.263 |
decidual artheriopathy (percentage) | 66.7 | 23.1 | 0.000 |
intervillous thrombi (percentage) | 53.8 | 38.5 | 0.177 |
chorangiosis (percentage) | 17.9 | 10.3 | 0.335 |
accelerated villous maturation (percentage) | 23.1 | 28.2 | 0.610 |
inflammatory infiltrate (percentage) | 69.2 | 46.2 | 0.040 |
no histopathological abnormalities (percentage) | 5.1 | 10.3 | 0.384 |
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Bobei, T.-I.; Sima, R.-M.; Gorecki, G.-P.; Poenaru, M.-O.; Olaru, O.-G.; Bobirca, A.; Cirstoveanu, C.; Chicea, R.; Topirceanu-Andreoiu, O.-M.; Ples, L. Placenta, the Key Witness of COVID-19 Infection in Premature Births. Diagnostics 2022, 12, 2323. https://doi.org/10.3390/diagnostics12102323
Bobei T-I, Sima R-M, Gorecki G-P, Poenaru M-O, Olaru O-G, Bobirca A, Cirstoveanu C, Chicea R, Topirceanu-Andreoiu O-M, Ples L. Placenta, the Key Witness of COVID-19 Infection in Premature Births. Diagnostics. 2022; 12(10):2323. https://doi.org/10.3390/diagnostics12102323
Chicago/Turabian StyleBobei, Tina-Ioana, Romina-Marina Sima, Gabriel-Petre Gorecki, Mircea-Octavian Poenaru, Octavian-Gabriel Olaru, Anca Bobirca, Catalin Cirstoveanu, Radu Chicea, Oana-Maria Topirceanu-Andreoiu, and Liana Ples. 2022. "Placenta, the Key Witness of COVID-19 Infection in Premature Births" Diagnostics 12, no. 10: 2323. https://doi.org/10.3390/diagnostics12102323