Risk Assessment of Endometrial Hyperplasia or Endometrial Cancer with Simplified Ultrasound-Based Scoring Systems
Abstract
1. Introduction
2. Materials and Methods
3. Results
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Age (years) | 60.3 ± 10.7 |
BMI (kg/m2) | 30.4 ± 6.0 |
BMI (kg/m2) ≥ 30 kg/m2 (n) | 180 [46%] |
Menopausal status | |
Postmenopausal (n) | 289 [73.4%] |
Premenopausal (n) | 105 [26.6%] |
n | % | |
---|---|---|
All patients | 394 | 100 |
Hyperplasia without atypia (SH) | 103 | 26.1 |
Atypical hyperplasia (AH) | 55 | 14 |
Endometrial Cancer (EC) | 236 | 59.9 |
Endometrioid EC (EEC) | 216 | 54.8 |
Non-endometrioid EC (NEC) | 20 | 5.1 |
Stage 1 | 152 | 38.57 |
Stage 2 | 47 | 11.93 |
Stage 3 | 30 | 7.61 |
Stage 4 | 7 | 1.77 |
ET ≥ 8 mm | 332 | 84.26 |
EC or AH in women with ET ≥ 8 mm (% of total number of EC/AH) | 263 | 90.37 |
n | AUC (95% CI) | Sensitivity (%) | Specificity (%) | Accuracy (%) | LR+ | LR− | |
---|---|---|---|---|---|---|---|
BMI | 394 | 59 (53–69) | |||||
BMI ≥ 30 | 180 | 58 (52–64) | 52 | 65 | 57 | 1.47 | 0.75 |
Endometrial thickness | 394 | 76 (71–81) | |||||
Endometrial thickness ≥8 | 332 | 60 (54–66) | 92 | 28 | 67 | 1.28 | 0.27 |
Endometrial thickness ≥10 | 299 | 65 (60–71) | 88 | 42 | 70 | 1.53 | 0.28 |
Endometrial thickness ≥15 | 221 | 68 (63–74) | 71 | 66 | 69 | 2.07 | 0.44 |
Heterogenic endometrium | 350 | 54 (48–60) | 14 | 94 | 46 | 2.28 | 0.91 |
Cystic endometrium | 67 | 55 (49–60) | 21 | 89 | 48 | 1.82 | 0.89 |
Interrupted endomyometrial junction (IEJ) | 182 | 70 (65–75) | 62 | 78 | 69 | 2.81 | 0.48 |
Vascularity, and more than one single or double dominant vessel (a) | 208 | 53 (48–59) | 56 | 51 | 54 | 1.14 | 0.87 |
Multiple endometrial vessels (b) | 110 | 61 (56–67) | 37 | 85 | 56 | 2.53 | 0.74 |
Large endometrial vessels (c) | 17 | 51 (45–57) | 5 | 97 | 42 | 1.61 | 0.98 |
Densely packed or color splash | 25 | 54 (48–59) | 9 | 98 | 45 | 4.91 | 0.92 |
Doppler score (a + b + c) | 394 | 58 (53–64) | |||||
Doppler score (a + b + c) ≥ 1 | 209 | 54 (48–59) | 56 | 51 | 54 | 1.15 | 0.86 |
Doppler score (a + b + c) ≥ 2 | 115 | 60 (55–66) | 37 | 83 | 56 | 2.18 | 0.76 |
n = 394 | AUC (95% CI) | Sensitivity (%) | Specificity (%) | Accuracy (%) | LR+ | LR− |
---|---|---|---|---|---|---|
Score A | 68 (62–73) | 72 | 71 | 72 | 2.47 | 0.40 |
REC | 75 (70–79) | 79 | 61 | 72 | 2.02 | 0.34 |
Basic Model [29] ET, Doppler score, IEJ | 77 (73–82) | 78 | 70 | 75 | 2.58 | 0.31 |
Model A [31] Doppler score, IEJ | 71 (66–76) | 72 | 70 | 71 | 2.36 | 0.41 |
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Stachowicz, N.; Smoleń, A.; Ciebiera, M.; Łoziński, T.; Poziemski, P.; Borowski, D.; Czekierdowski, A. Risk Assessment of Endometrial Hyperplasia or Endometrial Cancer with Simplified Ultrasound-Based Scoring Systems. Diagnostics 2021, 11, 442. https://doi.org/10.3390/diagnostics11030442
Stachowicz N, Smoleń A, Ciebiera M, Łoziński T, Poziemski P, Borowski D, Czekierdowski A. Risk Assessment of Endometrial Hyperplasia or Endometrial Cancer with Simplified Ultrasound-Based Scoring Systems. Diagnostics. 2021; 11(3):442. https://doi.org/10.3390/diagnostics11030442
Chicago/Turabian StyleStachowicz, Norbert, Agata Smoleń, Michał Ciebiera, Tomasz Łoziński, Paweł Poziemski, Dariusz Borowski, and Artur Czekierdowski. 2021. "Risk Assessment of Endometrial Hyperplasia or Endometrial Cancer with Simplified Ultrasound-Based Scoring Systems" Diagnostics 11, no. 3: 442. https://doi.org/10.3390/diagnostics11030442
APA StyleStachowicz, N., Smoleń, A., Ciebiera, M., Łoziński, T., Poziemski, P., Borowski, D., & Czekierdowski, A. (2021). Risk Assessment of Endometrial Hyperplasia or Endometrial Cancer with Simplified Ultrasound-Based Scoring Systems. Diagnostics, 11(3), 442. https://doi.org/10.3390/diagnostics11030442