A Rare Case of Allantoic Cyst with Patent Urachus in Fetus with a Microdeletion in 1q21.1q21.2 Region

Bouariu, Alexandra; Scutelnicu, Ana Maria; Ciobanu, Anca Marina; Cimpoca Raptis, Brîndușa Ana; Dumitru, Andreea Elena; Nedelea, Florina; Gică, Nicolae; Panaitescu, Anca Maria

doi:10.3390/diagnostics11122332

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A Rare Case of Allantoic Cyst with Patent Urachus in Fetus with a Microdeletion in 1q21.1q21.2 Region

by

Alexandra Bouariu

¹,

Ana Maria Scutelnicu

¹,

Anca Marina Ciobanu

^1,2,

Brîndușa Ana Cimpoca Raptis

^1,2,

Andreea Elena Dumitru

¹,

Florina Nedelea

^1,2,3,

Nicolae Gică

^1,2

and

Anca Maria Panaitescu

^1,2,*

¹

Filantropia Clinical Hospital Bucharest, 011117 Bucharest, Romania

²

Department of Obstetrics and Gynecology, “Carol Davila” University of Medicine and Pharmacy, 020021 Bucharest, Romania

³

Department of Human Genetics, Clinical Hospital Filantropia Bucharest, 011117 Bucharest, Romania

^*

Author to whom correspondence should be addressed.

Diagnostics 2021, 11(12), 2332; https://doi.org/10.3390/diagnostics11122332

Submission received: 25 October 2021 / Revised: 29 November 2021 / Accepted: 7 December 2021 / Published: 11 December 2021

(This article belongs to the Special Issue Imaging of Fetal and Maternal Diseases in Pregnancy)

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Abstract

An allantoic cyst is a rare malformation with a frequency of 3 in 1,000,000 that may be seen antenatally by ultrasound assessment when the connection between the cloaca (future bladder) and the allantois fails to regress. A patent urachus that presents as a cyst (allantoic) is usually considered not to be associated with chromosomal abnormalities, but if it is not repaired after birth this leads to complications such as urinary tract infections and stone formation. We present a case of a fetus diagnosed with allantoic cyst at the first trimester ultrasound assessment at 12 weeks gestation. The follow up scans showed a decrease in size of the allantoic cyst with no other obvious major defects and, when invasive testing (amniocentesis with microarray analysis) was performed, a rare microdeletion, 1q21.1q21.2 was identified (1.82 Mb deletion).

Keywords: allantoic cyst; umbilical cyst; fetal bladder; fetal ultrasound

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MDPI and ACS Style

Bouariu, A.; Scutelnicu, A.M.; Ciobanu, A.M.; Cimpoca Raptis, B.A.; Dumitru, A.E.; Nedelea, F.; Gică, N.; Panaitescu, A.M. A Rare Case of Allantoic Cyst with Patent Urachus in Fetus with a Microdeletion in 1q21.1q21.2 Region. Diagnostics 2021, 11, 2332. https://doi.org/10.3390/diagnostics11122332

AMA Style

Bouariu A, Scutelnicu AM, Ciobanu AM, Cimpoca Raptis BA, Dumitru AE, Nedelea F, Gică N, Panaitescu AM. A Rare Case of Allantoic Cyst with Patent Urachus in Fetus with a Microdeletion in 1q21.1q21.2 Region. Diagnostics. 2021; 11(12):2332. https://doi.org/10.3390/diagnostics11122332

Chicago/Turabian Style

Bouariu, Alexandra, Ana Maria Scutelnicu, Anca Marina Ciobanu, Brîndușa Ana Cimpoca Raptis, Andreea Elena Dumitru, Florina Nedelea, Nicolae Gică, and Anca Maria Panaitescu. 2021. "A Rare Case of Allantoic Cyst with Patent Urachus in Fetus with a Microdeletion in 1q21.1q21.2 Region" Diagnostics 11, no. 12: 2332. https://doi.org/10.3390/diagnostics11122332

APA Style

Bouariu, A., Scutelnicu, A. M., Ciobanu, A. M., Cimpoca Raptis, B. A., Dumitru, A. E., Nedelea, F., Gică, N., & Panaitescu, A. M. (2021). A Rare Case of Allantoic Cyst with Patent Urachus in Fetus with a Microdeletion in 1q21.1q21.2 Region. Diagnostics, 11(12), 2332. https://doi.org/10.3390/diagnostics11122332

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A Rare Case of Allantoic Cyst with Patent Urachus in Fetus with a Microdeletion in 1q21.1q21.2 Region

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