Characterization of Uterine Motion in Early Gestation Using MRI-Based Motion Tracking
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Population
2.2. MRI Techniques and Reconstruction
2.3. Image-Based Template-Matching Motion Tracking
2.4. Uterine Contraction and Maternal Motion
2.5. Statistical Analysis
3. Results
3.1. Uterine Contraction
3.2. Maternal Motion
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Conflicts of Interest
References
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Imaging Parameters | 3-D Multi-Echo GA Radial GRE |
---|---|
Number of Echoes | 6–12 |
TE1, ms | 1.23 |
ΔTE, ms | 1.23 |
TR, ms | 8.85–15.9 |
In-plane Resolution, mm × mm | 1.7–2.2 × 1.7–2.2 |
FOV, mm | 350–380 |
Slice Thickness, mm | 3.5–5 |
Flip Angle, degrees | 5 |
Scan Time, min: sec | 3:18–6:06 |
Groups | Uterine Contraction | Number of Contraction/Totals (%) | Maternal Motion | |||
---|---|---|---|---|---|---|
GA, Weeks | p-Value | GA, Weeks | p-Value | |||
All Cases | 19.0 ± 2.6 | 25/112 (22.3) | 17.8 ± 2.6 | |||
Longitudinal | 1st MRI | 16.5 ± 1.0 | <0.001 ** | 11/59 (18.6) | 15.8 ± 1.0 | <0.001 ** |
2nd MRI | 20.9 ± 1.4 | 14/53 (26.4) | 20.4 ± 1.2 | |||
Fetal Sex | Female | 18.8 ± 2.4 | 1 | 11/50 (22.0) | 18.0 ± 2.6 | 0.57 |
Male | 19.1 ± 2.8 | 14/62 (22.6) | 17.7 ± 2.5 | |||
Placental Position | Anterior | 18.9 ± 2.3 | 0.87 | 12/60 (20.0) | 18.0 ± 2.6 | 0.51 |
Posterior | 19.0 ± 2.9 | 13/52 (25.0) | 17.7 ± 2.5 |
Groups | AUCnorm, mm | p-Value | Umax, mm | p-Value | θ, Degrees | Number of SI Dominant/Totals (%) | |
---|---|---|---|---|---|---|---|
All Cases | 3.1 ± 2.0 | 7.8 ± 5.5 | 66.7 ± 18.1 | 21/25 (84) | |||
Longitudinal | 1st MRI | 3.3 ± 2.1 | 0.76 | 6.7 ± 4.3 | 0.46 | 69.3 ± 17.7 | 10/11 (90.9) |
2nd MRI | 3.0 ± 1.9 | 8.7 ± 6.3 | 64.7 ± 18.9 | 11/14 (78.6) | |||
Fetal Sex | Female | 2.8 ± 2.2 | 0.20 | 7.4 ± 4.2 | 0.94 | 72.6 ± 14.4 | 10/11 (90.9) |
Male | 3.4 ± 1.8 | 8.1 ± 6.4 | 62.0 ± 19.9 | 11/14 (78.6) | |||
Placental Position | Anterior | 3.2 ± 2.2 | 0.98 | 8.0 ± 4.8 | 0.61 | 65.4 ± 16.7 | 10/12 (83.3) |
Posterior | 3.0 ± 1.9 | 7.6 ± 6.2 | 67.9 ± 19.9 | 11/13 (84.6) |
Groups | Umax, mm | p-Value | θ, Degrees | Number of SI Dominant/Totals (%) | |
---|---|---|---|---|---|
All Cases | 2.1 ± 2.1 | 60.0 ± 29.9 | 59/87 (67.8) | ||
Longitudinal | 1st MRI | 1.8 ± 1.2 | 0.48 | 65.7 ± 29.9 | 35/48 (72.9) |
2nd MRI | 2.4 ± 2.8 | 52.9 ± 28.7 | 24/39 (61.5) | ||
Fetal Sex | Female | 2.2 ± 2.7 | 0.77 | 61.2 ± 29.2 | 27/39 (69.2) |
Male | 2.0 ± 1.4 | 59.0 ± 30.7 | 32/48 (66.7) | ||
Placental Position | Anterior | 2.0 ± 1.5 | 0.50 | 58.0 ± 30.3 | 30/48 (62.5) |
Posterior | 2.1 ± 2.6 | 62.3 ± 29.5 | 29/39 (74.3) |
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Martin, T.; Janzen, C.; Li, X.; Del Rosario, I.; Chanlaw, T.; Choi, S.; Armstrong, T.; Masamed, R.; Wu, H.H.; Devaskar, S.U.; et al. Characterization of Uterine Motion in Early Gestation Using MRI-Based Motion Tracking. Diagnostics 2020, 10, 840. https://doi.org/10.3390/diagnostics10100840
Martin T, Janzen C, Li X, Del Rosario I, Chanlaw T, Choi S, Armstrong T, Masamed R, Wu HH, Devaskar SU, et al. Characterization of Uterine Motion in Early Gestation Using MRI-Based Motion Tracking. Diagnostics. 2020; 10(10):840. https://doi.org/10.3390/diagnostics10100840
Chicago/Turabian StyleMartin, Thomas, Carla Janzen, Xinzhou Li, Irish Del Rosario, Teresa Chanlaw, Sarah Choi, Tess Armstrong, Rinat Masamed, Holden H. Wu, Sherin U. Devaskar, and et al. 2020. "Characterization of Uterine Motion in Early Gestation Using MRI-Based Motion Tracking" Diagnostics 10, no. 10: 840. https://doi.org/10.3390/diagnostics10100840