Evaluation of Primary Correction and Its Influencing Factors in Adolescent Idiopathic Scoliosis After Treatment with the Charleston Bending Brace as the Sole Intervention
Abstract
1. Introduction
2. Materials and Methods
Statistical Analysis
3. Results
3.1. Overall Curve Correction of the Major Curve During Follow-Up
3.2. Group-Specific Primary Curve Correction After t1 in the Brace
3.3. Group-Specific Curve Correction During Follow-Up
4. Discussion
5. Conclusions
6. Limitations
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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No. of Patients | Percentage | Cobb Angle | |||
---|---|---|---|---|---|
Median | Maximum | Minimum | |||
Major curve | 97 | 100 | 25.7° | 60.8° | 10.7° |
Minor curve | 42 | 43.3 | 23.45° | 43.4° | 12.6° |
Major curve in subgroups: | |||||
S-shaped: no | 55 | 56.7 | 25.0 | 60.8 | 10.7 |
S-shaped: yes | 42 | 43.3 | 32.8 | 51.9 | 15.5 |
Lumbar major curve | 49 | 50.5 | 23.5° | 45.4° | 10.7° |
Thoracic major curve | 48 | 49.5 | 33.9° | 60.8° | 16.5° |
Female | 70 | 72.2 | 25.8° | 55.5° | 10.7° |
Male | 27 | 27.8 | 25.3° | 60.8° | 17.7° |
Lenke 1 | 51 | 52.6 | 26.0° | 60.8° | 15.5° |
Lenke 2 | 15 | 15.5 | 42.2° | 51.9° | 21.4° |
Lenke 3 | 1 | 1.0 | 44.4° | 44.4° | 44.4° |
Lenke 5 | 30 | 30.9 | 23.6° | 34.4° | 10.7° |
Risser Stage 0 | 26 | 26.8 | 25.0° | 46.1° | 15.5° |
Risser Stage 1 | 7 | 7.2 | 26° | 48.4° | 16.5° |
Risser Stage 2 | 25 | 25.8 | 25.3° | 55.5° | 10.7° |
Risser Stage 3 | 28 | 28.9 | 26.05° | 60.8° | 17.4° |
Risser Stage 4 | 10 | 10.3 | 36.45° | 48.4° | 21.3° |
Risser Stage 5 | 1 | 1.0 | 21.9° | 21.9° | 21.9° |
Nash–Moe 1 | 68 | 70.1 | 24.3° | 48.4° | 10.7° |
Nash–Moe 2 | 28 | 28.9 | 35.5° | 55.5° | 19.4° |
Nash–Moe 3 | 1 | 1.0 | 60.8° | 60.8° | 60.8° |
Menarche: no | 51 | 72.9 | 25.4° | 51.9° | 10.7° |
Menarche: yes | 19 | 27.1 | 28.1° | 55.5° | 17.4° |
n | Median in % | Worst in % | Best in % | p-Value | |
---|---|---|---|---|---|
Major curve | 97 | 74.2 | 12.9 | 100.0 | p = 0.066 * |
Minor curve | 42 | 67.3 | 2.3 | 100.0 | |
Major curve compared in subgroups: | |||||
S-shaped: no | 55 | 91.6 | 12.9 | 100.0 | p = 0.015 * |
S-shaped: yes | 42 | 67.1 | 21.7 | 100.0 | |
Lumbar major curve | 49 | 100.0 | 18.7 | 100.0 | p < 0.001 * |
Thoracic major curve | 48 | 53.9 | 12.9 | 100.0 | |
Female | 70 | 71.4 | 13.3 | 100.0 | p = 0.443 * |
Male | 27 | 74.8 | 12.9 | 100.0 | |
Lenke 1 | 51 | 67.6 | 12.9 | 100.0 | p < 0.001 ** |
Lenke 2 | 15 | 46.7 | 21.7 | 100.0 | |
Lenke 3 | 1 | 69.2 | 69.2 | 69.2 | |
Lenke 5 | 30 | 100.0 | 45.3 | 100.0 | |
Risser 0 | 26 | 84.9 | 12.9 | 100.0 | p = 0.067 ** |
Risser 1 | 7 | 51.0 | 37.7 | 100.0 | |
Risser 2 | 25 | 100.0 | 29.8 | 100.0 | |
Risser 3 | 28 | 65.6 | 13.3 | 100.0 | |
Risser 4 | 10 | 54.7 | 28.9 | 100.0 | |
Risser 5 | 1 | 100.0 | 100.0 | 100.0 | |
Nash–Moe 1 | 68 | 89.3 | 13.3 | 100.0 | p = 0.005 * |
Nash–Moe 2 | 28 | 63.4 | 12.9 | 100.0 | |
Nash–Moe 3 | 1 | 53.9 | 53.9 | 53.9 | |
Menarche: no | 51 | 71.1 | 18.7 | 100.0 | p = 0.731 * |
Menarche: yes | 19 | 71.7 | 13.3 | 100.0 | |
* Mann–Whitney U test | |||||
** Kruskal–Wallis test |
N t2 | t2: Median [Worst; Best] in % | p-Value | N t3 | t3: Median [Worst; Best] in % | p-Value | |
---|---|---|---|---|---|---|
Major curve | 27 | 17.3 [−22.1; 50.1] | 28 | 9.9 [−46.9; 100.0] | ||
Major curve compared in subgroups: | ||||||
Lumbar major curve | 16 | 19.2 [−9.2; 47.7] | p = 0.622 # | 16 | 9.3 [−46.9; 100.0] | p = 0.708 # |
Thoracic major curve | 11 | 17.3 [−22.1; 50.1] | 12 | 14.7 [−35.2; 51.8] | ||
Female | 16 | 16.6 [−9.2; 50.1] | p = 0.823 # | 20 | 9.3 [−46.9; 100.0] | p = 0.916 # |
Male | 11 | 17.3 [−22.1; 42.0] | 8 | 14.7 [−35.2; 66.0] | ||
Lenke 1 | 16 | 19.2 [−22.1; 50.1] | p = 0.757 # | 17 | 10.5 [−46.9; 100.0] | p = 0.647 # |
Lenke 2 | 1 | 22.9 | (Lenke 1 vs. 5) | |||
Lenke 5 | 10 | 16.3 [2.5; 31.7] | 11 | 9.3 [−13.3; 66.0] | ||
Risser 0 | 9 | 16.2 [2.5; 47.7] | p = 0.546 ** | 9 | 10.5 [−21.8; 66.0] | p = 0.799 ## |
Risser 1 | 3 | 9.3 [−12.4; 37.5] | ||||
Risser 2 | 9 | 22.0 [9.2; 50.1] | 8 | 23.7 [1.2; 38.3] | ||
Risser 3 | 6 | 24.2 [7.8; 38.6] | 6 | 3.5 [−46.9; 100.0] | ||
Risser 4 | 3 | 4.5 [−22.1; 28.9] | 2 | −12.9 [−31.5; 9.3] | ||
Nash–Moe 1 | 18 | 16.8 [−22.1; 47.7] | p = 0.492 # | 15 | 19.1 [−35.2; 100.0] | p = 0.201 * |
Nash–Moe 2 | 9 | 24.8 [4.5; 50.1] | 13 | 9.3 [−46.9; 24.1] | ||
Menarche: no | 11 | 8.7 [−9.2; 47.7] | p = 0.451 # | 16 | 0.4 [−46.9; 51.8] | p = 0.061 # |
Menarche: yes | 5 | 28.9 [4.5; 50.1] | 4 | 22.9 [9.3; 100.0] | ||
Parametric tests: | # unpaired t test or ## ANOVA | |||||
Non-parametric tests: | * Mann–Whitney U test or ** Kruskal–Wallis test |
N t3 | Number of Patients with Progression in Out-of-Brace Radiograph at t3 (%) | Number of Patients with Progression ≥ 6° in Out-of-Brace Radiograph at t3 (%) | |
---|---|---|---|
Initial in-brace correction at t1: | |||
≤80% (n = 55; 56.7%) | 16 | 7 (43.8%) | 3 (18.8%) |
>80% (n = 42; 43.3%) | 12 | 2 (16.7%) | 0 (0%) |
p-value (Fisher’s exact test) | p = 0.223 | p = 0.238 |
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Froehlich, S.; Klinder, A.; Stirn, M.; Mittelmeier, W.; Osmanski-Zenk, K. Evaluation of Primary Correction and Its Influencing Factors in Adolescent Idiopathic Scoliosis After Treatment with the Charleston Bending Brace as the Sole Intervention. Life 2025, 15, 448. https://doi.org/10.3390/life15030448
Froehlich S, Klinder A, Stirn M, Mittelmeier W, Osmanski-Zenk K. Evaluation of Primary Correction and Its Influencing Factors in Adolescent Idiopathic Scoliosis After Treatment with the Charleston Bending Brace as the Sole Intervention. Life. 2025; 15(3):448. https://doi.org/10.3390/life15030448
Chicago/Turabian StyleFroehlich, Susanne, Annett Klinder, Morris Stirn, Wolfram Mittelmeier, and Katrin Osmanski-Zenk. 2025. "Evaluation of Primary Correction and Its Influencing Factors in Adolescent Idiopathic Scoliosis After Treatment with the Charleston Bending Brace as the Sole Intervention" Life 15, no. 3: 448. https://doi.org/10.3390/life15030448
APA StyleFroehlich, S., Klinder, A., Stirn, M., Mittelmeier, W., & Osmanski-Zenk, K. (2025). Evaluation of Primary Correction and Its Influencing Factors in Adolescent Idiopathic Scoliosis After Treatment with the Charleston Bending Brace as the Sole Intervention. Life, 15(3), 448. https://doi.org/10.3390/life15030448