Biodistribution Assessment of a Novel 68Ga-Labeled Radiopharmaceutical in a Cancer Overexpressing CCK2R Mouse Model: Conventional and Radiomics Methods for Analysis
Abstract
:1. Introduction
2. Materials and Methods
2.1. Ethics Statement and Animal Model
2.2. Immunohistochemistry Staining and Digital Pathology Evaluation
2.3. Radiopharmaceutical
2.4. PET/CT
2.5. Atlas-Based Multi-Organ Segmentation
2.6. Radiomics Feature Extraction and Analyses
3. Results and Discussion
4. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Pavone, A.M.; Benfante, V.; Giaccone, P.; Stefano, A.; Torrisi, F.; Russo, V.; Serafini, D.; Richiusa, S.; Pometti, M.; Scopelliti, F.; et al. Biodistribution Assessment of a Novel 68Ga-Labeled Radiopharmaceutical in a Cancer Overexpressing CCK2R Mouse Model: Conventional and Radiomics Methods for Analysis. Life 2024, 14, 409. https://doi.org/10.3390/life14030409
Pavone AM, Benfante V, Giaccone P, Stefano A, Torrisi F, Russo V, Serafini D, Richiusa S, Pometti M, Scopelliti F, et al. Biodistribution Assessment of a Novel 68Ga-Labeled Radiopharmaceutical in a Cancer Overexpressing CCK2R Mouse Model: Conventional and Radiomics Methods for Analysis. Life. 2024; 14(3):409. https://doi.org/10.3390/life14030409
Chicago/Turabian StylePavone, Anna Maria, Viviana Benfante, Paolo Giaccone, Alessandro Stefano, Filippo Torrisi, Vincenzo Russo, Davide Serafini, Selene Richiusa, Marco Pometti, Fabrizio Scopelliti, and et al. 2024. "Biodistribution Assessment of a Novel 68Ga-Labeled Radiopharmaceutical in a Cancer Overexpressing CCK2R Mouse Model: Conventional and Radiomics Methods for Analysis" Life 14, no. 3: 409. https://doi.org/10.3390/life14030409