Next Article in Journal
Alternative Enzyme Inhibition Assay for Safety Evaluation of Food Preservatives
Next Article in Special Issue
Three-Dimensional Visualization System for Vitreoretinal Surgery: Results from a Monocentric Experience and Comparison with Conventional Surgery
Previous Article in Journal
The Quantification of Bacterial Cell Size: Discrepancies Arise from Varied Quantification Methods
Previous Article in Special Issue
Micropulse Transscleral Cyclophotocoagulation Results in Secondary Glaucoma
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Life
Volume 13
Issue 6
10.3390/life13061241
life-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Review

Pars Plana Vitrectomy in Inherited Retinal Diseases: A Comprehensive Review of the Literature

by
Claudio Iovino
,
Andrea Rosolia
,
Luciana Damiano
,
Clemente Maria Iodice
,
Valentina Di Iorio
,
Francesco Testa
* and
Francesca Simonelli
Eye Clinic, Multidisciplinary Department of Medical, Surgical and Dental Sciences, University of Campania Luigi Vanvitelli, 80131 Naples, Italy
*
Author to whom correspondence should be addressed.
Life 2023, 13(6), 1241; https://doi.org/10.3390/life13061241
Submission received: 16 March 2023 / Revised: 4 May 2023 / Accepted: 21 May 2023 / Published: 24 May 2023
(This article belongs to the Collection New Diagnostic and Therapeutic Developments in Eye Diseases)
Browse Figures
Versions Notes

Abstract

Inherited retinal diseases (IRDs) are a group of clinically and genetically heterogeneous disorders that may be complicated by several vitreoretinal conditions requiring a surgical approach. Pars plana vitrectomy (PPV) stands as a valuable treatment option in these cases, but its application in eyes with such severely impaired chorioretinal architectures remains controversial. Furthermore, the spreading of gene therapy and the increasing use of retinal prostheses will end up in a marked increase in demand for PPV surgery for IRD patients. The retinal degeneration that typically affects patients with hereditary retinal disorders may influence the execution of the surgery and the expected results. Considering the importance of PPV application in IRD-related complications, it is fundamental to try to understand from the literature what is adequate and safe in posterior eye segment surgery. Use of dyes, light toxicity, and risk of wounding scar development have always been themes that discourage the execution of vitreoretinal surgery in already impaired eyes. Therefore, this review aims to comprehensively summarize all PPV applications in different IRDs, highlighting the favorable results as well as the potential precautions to consider when performing vitreoretinal surgery in these eyes.
Keywords: best disease; choroideremia; familiar exudative vitreoretinopathy; pars plana vitrectomy; retinitis pigmentosa; Stargardt disease; X-linked retinoschisis best disease; choroideremia; familiar exudative vitreoretinopathy; pars plana vitrectomy; retinitis pigmentosa; Stargardt disease; X-linked retinoschisis

Share and Cite

MDPI and ACS Style

Iovino, C.; Rosolia, A.; Damiano, L.; Iodice, C.M.; Di Iorio, V.; Testa, F.; Simonelli, F. Pars Plana Vitrectomy in Inherited Retinal Diseases: A Comprehensive Review of the Literature. Life 2023, 13, 1241. https://doi.org/10.3390/life13061241

AMA Style

Iovino C, Rosolia A, Damiano L, Iodice CM, Di Iorio V, Testa F, Simonelli F. Pars Plana Vitrectomy in Inherited Retinal Diseases: A Comprehensive Review of the Literature. Life. 2023; 13(6):1241. https://doi.org/10.3390/life13061241

Chicago/Turabian Style

Iovino, Claudio, Andrea Rosolia, Luciana Damiano, Clemente Maria Iodice, Valentina Di Iorio, Francesco Testa, and Francesca Simonelli. 2023. "Pars Plana Vitrectomy in Inherited Retinal Diseases: A Comprehensive Review of the Literature" Life 13, no. 6: 1241. https://doi.org/10.3390/life13061241

APA Style

Iovino, C., Rosolia, A., Damiano, L., Iodice, C. M., Di Iorio, V., Testa, F., & Simonelli, F. (2023). Pars Plana Vitrectomy in Inherited Retinal Diseases: A Comprehensive Review of the Literature. Life, 13(6), 1241. https://doi.org/10.3390/life13061241

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop