Structure, Activity and Function of the PRMT2 Protein Arginine Methyltransferase
Abstract
:1. Introduction
2. Structural features
2.1. Sequence
2.2. Structure
2.3. Co-Factor Binding Site
2.4. Substrate Binding Pocket
2.5. Dimerization
3. Activity
4. Interactions
4.1. Coactivation
4.2. Splicing
5. Diseases
5.1. Breast Cancer
5.2. Other Pathologies
6. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Acknowledgments
Conflicts of Interest
References
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Cura, V.; Cavarelli, J. Structure, Activity and Function of the PRMT2 Protein Arginine Methyltransferase. Life 2021, 11, 1263. https://doi.org/10.3390/life11111263
Cura V, Cavarelli J. Structure, Activity and Function of the PRMT2 Protein Arginine Methyltransferase. Life. 2021; 11(11):1263. https://doi.org/10.3390/life11111263
Chicago/Turabian StyleCura, Vincent, and Jean Cavarelli. 2021. "Structure, Activity and Function of the PRMT2 Protein Arginine Methyltransferase" Life 11, no. 11: 1263. https://doi.org/10.3390/life11111263