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Antibodies, Volume 3, Issue 4

December 2014 - 2 articles

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Review

2 Citations

8,126 Views

14 Pages

Antibody Fragments Defining Biologically Relevant Conformations of Target Proteins

Alastair D. G. Lawson

Antibodies2014, 3(4), 289-302;https://doi.org/10.3390/antib3040289

11 December 2014

Antibody fragments have long been used as chaperones in crystallography, but have more recently been applied to the definition of biologically relevant conformations among the dynamic ensemble of target protein conformational sampling. This review ch...

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Article

4 Citations

8,435 Views

17 Pages

Polyclonal Antibody Therapies for Clostridium difficile Infection

Michael R. Simon,
Stephanie M. Chervin and
Stephen C. Brown

Antibodies2014, 3(4), 272-288;https://doi.org/10.3390/antib3040272

28 October 2014

Clostridium difficile infection has emerged as a growing worldwide health problem. The colitis of Clostridium difficile infection results from the synergistic action of C. difficile secreted toxins A and B upon the colon mucosa. A human monoclonal Ig...

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