Next Article in Journal
Did ERA5 Improve Temperature and Precipitation Reanalysis over East Africa?
Previous Article in Journal
Helicopter Pilots Encountering Fog: An Analysis of 109 Accidents from 1992 to 2016
Open AccessEditorial

May SARS-CoV-2 Diffusion Be Favored by Alkaline Aerosols and Ammonia Emissions?

Department of Technological Innovations, INAIL, Via IV Novembre 144, I-00187 Rome, Italy
Department of Public Health and Infectious Diseases, University of Rome La Sapienza, P.le Aldo Moro, 5, I-00185 Rome, Italy
Institute of Atmospheric Pollution Research, National Research Council, Rome Research Area-Montelibretti, I-00015 Monterotondo Scalo, Italy
Department of Agricultural, Environmental and Food Sciences (DiAAA), University of Molise, via F. De Sanctis, I-86100 Campobasso, Italy
Authors to whom correspondence should be addressed.
Atmosphere 2020, 11(9), 995;
Received: 13 September 2020 / Accepted: 15 September 2020 / Published: 17 September 2020
Ammonia is a common factor linking air in bat caves and air pollution in the proximity of agricultural fields treated with livestock farming sewage and slaughterhouses, where important clusters of COVID-19 have recently been reported all over the world. Such a commonality has a further connection with the known behavior of some viruses of the coronavirus family, such as the murine hepatitis virus, whose spike glycoprotein (S) can be triggered to a membrane-binding conformation at pH 8.0. Within the airborne route of virus transmission, with particular relevance for crowded and enclosed environments, these observations have prompted a hypothesis that may represent a contributing cause to interpret the geographical variability of the virus diffusion and the surging rise of COVID-19 cases in slaughterhouses all over the world. The hypothesis is that, in these environments, the SARS-CoV-2 S protein may find on a fraction of the airborne particles an alkaline pH, favorable to trigger the conformational changes, needed to induce the fusion of the viral envelope with the plasma membrane of the target cells. View Full-Text
Keywords: SARS-Cov-2; aerosol; ammonia; pH; livestock farming sewage; slaughterhouses SARS-Cov-2; aerosol; ammonia; pH; livestock farming sewage; slaughterhouses
MDPI and ACS Style

Manigrasso, M.; Protano, C.; Guerriero, E.; Vitali, M.; Avino, P. May SARS-CoV-2 Diffusion Be Favored by Alkaline Aerosols and Ammonia Emissions? Atmosphere 2020, 11, 995.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

Search more from Scilit
Back to TopTop