Next Article in Journal
Mechanisms of DNA Methyltransferase Recruitment in Mammals
Next Article in Special Issue
PIF-Mediated Sucrose Regulation of the Circadian Oscillator is Light Quality and Temperature Dependent
Previous Article in Journal
Repetitive Fragile Sites: Centromere Satellite DNA as a Source of Genome Instability in Human Diseases
Previous Article in Special Issue
A Functional Connection between the Circadian Clock and Hormonal Timing in Arabidopsis
Article Menu
Issue 12 (December) cover image

Export Article

Open AccessReview
Genes 2018, 9(12), 616; https://doi.org/10.3390/genes9120616

Beyond Transcription: Fine-Tuning of Circadian Timekeeping by Post-Transcriptional Regulation

1
Fundación Instituto Leloir, Av. Patricias Argentinas, Buenos Aires C1405BWE, Argentina
2
RNA Biology and Molecular Physiology, Faculty for Biology, Bielefeld University, Universitaetsstrasse 25, D-33615 Bielefeld, Germany
*
Authors to whom correspondence should be addressed.
Received: 6 November 2018 / Revised: 29 November 2018 / Accepted: 3 December 2018 / Published: 10 December 2018
(This article belongs to the Special Issue Genetic Regulation of Circadian Rhythm in Plants)
Full-Text   |   PDF [1869 KB, uploaded 14 December 2018]   |  
  |   Review Reports

Abstract

The circadian clock is an important endogenous timekeeper, helping plants to prepare for the periodic changes of light and darkness in their environment. The clockwork of this molecular timer is made up of clock proteins that regulate transcription of their own genes with a 24 h rhythm. Furthermore, the rhythmically expressed clock proteins regulate time-of-day dependent transcription of downstream genes, causing messenger RNA (mRNA) oscillations of a large part of the transcriptome. On top of the transcriptional regulation by the clock, circadian rhythms in mRNAs rely in large parts on post-transcriptional regulation, including alternative pre-mRNA splicing, mRNA degradation, and translational control. Here, we present recent insights into the contribution of post-transcriptional regulation to core clock function and to regulation of circadian gene expression in Arabidopsis thaliana. View Full-Text
Keywords: circadian; post-transcriptional; RNA; splicing; RNA-binding proteins circadian; post-transcriptional; RNA; splicing; RNA-binding proteins
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
SciFeed

Share & Cite This Article

MDPI and ACS Style

Mateos, J.L.; De Leone, M.J.; Torchio, J.; Reichel, M.; Staiger, D. Beyond Transcription: Fine-Tuning of Circadian Timekeeping by Post-Transcriptional Regulation. Genes 2018, 9, 616.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Genes EISSN 2073-4425 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top