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Regulation and Functions of ROP GTPases in Plant–Microbe Interactions

Phytopathology, TUM School of Life Sciences Weihenstephan, Technical University of Munich, Emil-Ramann-Straße 2, 85354 Freising, Germany
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Cells 2020, 9(9), 2016; https://doi.org/10.3390/cells9092016
Received: 28 July 2020 / Revised: 28 August 2020 / Accepted: 31 August 2020 / Published: 2 September 2020
(This article belongs to the Special Issue Rho family of GTPases in Model Organisms and Systems)
Rho proteins of plants (ROPs) form a specific clade of Rho GTPases, which are involved in either plant immunity or susceptibility to diseases. They are intensively studied in grass host plants, in which ROPs are signaling hubs downstream of both cell surface immune receptor kinases and intracellular nucleotide-binding leucine-rich repeat receptors, which activate major branches of plant immune signaling. Additionally, invasive fungal pathogens may co-opt the function of ROPs for manipulation of the cytoskeleton, cell invasion and host cell developmental reprogramming, which promote pathogenic colonization. Strikingly, mammalian bacterial pathogens also initiate both effector-triggered susceptibility for cell invasion and effector-triggered immunity via Rho GTPases. In this review, we summarize central concepts of Rho signaling in disease and immunity of plants and briefly compare them to important findings in the mammalian research field. We focus on Rho activation, downstream signaling and cellular reorganization under control of Rho proteins involved in disease progression and pathogen resistance. View Full-Text
Keywords: Arabidopsis; barley; plant immunity; ROP GTPase; rice; disease susceptibility Arabidopsis; barley; plant immunity; ROP GTPase; rice; disease susceptibility
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MDPI and ACS Style

Engelhardt, S.; Trutzenberg, A.; Hückelhoven, R. Regulation and Functions of ROP GTPases in Plant–Microbe Interactions. Cells 2020, 9, 2016.

AMA Style

Engelhardt S, Trutzenberg A, Hückelhoven R. Regulation and Functions of ROP GTPases in Plant–Microbe Interactions. Cells. 2020; 9(9):2016.

Chicago/Turabian Style

Engelhardt, Stefan; Trutzenberg, Adriana; Hückelhoven, Ralph. 2020. "Regulation and Functions of ROP GTPases in Plant–Microbe Interactions" Cells 9, no. 9: 2016.

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Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

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