Cell Sheets Restore Secretory Function in Wounded Mouse Submandibular Glands
Abstract
:1. Introduction
2. Materials and Methods
2.1. Materials
2.2. Animals
2.3. Cell Sheet Preparation
2.4. Wounded SMG Mouse Model
2.5. Histological Studies
2.6. Confocal Analysis
2.7. Saliva Flow Rate
2.8. Saliva Protein Composition
3. Results
3.1. Treatment with Cell Sheets Promotes Tissue Organization
3.2. Treatment with Cell Sheets Promotes Epithelial Polarization
3.3. Treatment with Cell Sheets Promotes Secretory Function
4. Discussion
Supplementary Materials
Author Contributions
Funding
Conflicts of Interest
References
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dos Santos, H.T.; Kim, K.; Okano, T.; Camden, J.M.; Weisman, G.A.; Baker, O.J.; Nam, K. Cell Sheets Restore Secretory Function in Wounded Mouse Submandibular Glands. Cells 2020, 9, 2645. https://doi.org/10.3390/cells9122645
dos Santos HT, Kim K, Okano T, Camden JM, Weisman GA, Baker OJ, Nam K. Cell Sheets Restore Secretory Function in Wounded Mouse Submandibular Glands. Cells. 2020; 9(12):2645. https://doi.org/10.3390/cells9122645
Chicago/Turabian Styledos Santos, Harim T., Kyungsook Kim, Teruo Okano, Jean M. Camden, Gary A. Weisman, Olga J. Baker, and Kihoon Nam. 2020. "Cell Sheets Restore Secretory Function in Wounded Mouse Submandibular Glands" Cells 9, no. 12: 2645. https://doi.org/10.3390/cells9122645