Next Article in Journal
Clinical Development of PARP Inhibitors in Treating Metastatic Castration-Resistant Prostate Cancer
Next Article in Special Issue
miR-263b Controls Circadian Behavior and the Structural Plasticity of Pacemaker Neurons by Regulating the LIM-Only Protein Beadex
Previous Article in Journal
The Transcription Factor Elf3 Is Essential for a Successful Mesenchymal to Epithelial Transition
Previous Article in Special Issue
MiR-200-3p Is Potentially Involved in Cell Cycle Arrest by Regulating Cyclin A during Aestivation in Apostichopus japonicus
Open AccessReview

MicroRNAs in Obesity and Related Metabolic Disorders

Aix Marseille Univ, INSERM, INRA, C2VN, 13005 Marseille, France
Author to whom correspondence should be addressed.
Cells 2019, 8(8), 859;
Received: 22 July 2019 / Revised: 1 August 2019 / Accepted: 7 August 2019 / Published: 9 August 2019
(This article belongs to the Special Issue Regulatory Functions of microRNAs)
Metabolic disorders are characterized by the inability to properly use and/or store energy. The burdens of metabolic disease, such as obesity or diabetes, are believed to arise through a complex interplay between genetics and epigenetics predisposition, environment and nutrition. Therefore, understanding the molecular mechanisms for the onset of metabolic disease will provide new insights for prevention and treatment. There is growing concern about the dysregulation of micro-RNAs (miRNAs) in metabolic diseases. MiRNAs are short non-coding RNA molecules that post-transcriptionally repress the expression of genes by binding to untranslated regions and coding sequences of the target mRNAs. This review aims to provide recent data about the potential involvement of miRNAs in metabolic diseases, particularly obesity and type 2 diabetes. View Full-Text
Keywords: micro-RNA; obesity; diabetes; adipose tissue; pancreas; inflammation; leptin micro-RNA; obesity; diabetes; adipose tissue; pancreas; inflammation; leptin
Show Figures

Figure 1

MDPI and ACS Style

Landrier, J.-F.; Derghal, A.; Mounien, L. MicroRNAs in Obesity and Related Metabolic Disorders. Cells 2019, 8, 859.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map

Back to TopTop