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Polymers 2017, 9(8), 376; https://doi.org/10.3390/polym9080376

Effect of Catechol Content in Catechol-Conjugated Dextrans on Antiplatelet Performance

Department of Chemistry, Chungbuk National University, Chungbuk 28644, Korea
These authors equally contributed to this work.
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Received: 26 June 2017 / Revised: 17 August 2017 / Accepted: 17 August 2017 / Published: 19 August 2017
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Abstract

The surface coating of solid substrates using dextrans has gained a great deal of attention, because dextran-coated surfaces show excellent anti-fouling property as well as biocompatibility behavior. Much effort has been made to develop efficient methods for grafting dextrans on solid surfaces. This led to the development of catechol-conjugated dextrans (Dex-C) which can adhere to a number of solid surfaces, inspired by the underwater adhesion behavior of marine mussels. The present study is a systematic investigation of the characteristics of surface coatings developed with Dex-C. Various Dex-C with different catechol contents were synthesized and used as a surface coating material. The effect of catechol content on surface coating and antiplatelet performance was investigated. View Full-Text
Keywords: dextran; catechol conjugation; surface coating; antiplatelet dextran; catechol conjugation; surface coating; antiplatelet
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Jeong, Y.; Kim, K.-A.; Kang, S.M. Effect of Catechol Content in Catechol-Conjugated Dextrans on Antiplatelet Performance. Polymers 2017, 9, 376.

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