Next Article in Journal
Aerosol-Assisted Fast Formulating Uniform Pharmaceutical Polymer Microparticles with Variable Properties toward pH-Sensitive Controlled Drug Release
Next Article in Special Issue
pH- and Metal Ion- Sensitive Hydrogels based on N-[2-(dimethylaminoethyl)acrylamide]
Previous Article in Journal
Differentiation of Dental Pulp Stem Cells on Gutta-Percha Scaffolds
Previous Article in Special Issue
Amyloid Beta Aggregation in the Presence of Temperature-Sensitive Polymers
Open AccessArticle

Polyester-Based, Biodegradable Core-Multishell Nanocarriers for the Transport of Hydrophobic Drugs

Institute of Chemistry and Biochemistry, Freie Universität Berlin, Takustr. 3, 14195 Berlin, Germany
Laboratoire de Photochimie et d’Ingénierie Macromoléculaires, Université de Haute Alsace, 3 rue Alfred Werner, 68093 Mulhouse Cedex, France
Author to whom correspondence should be addressed.
Academic Editors: André Laschewsky and Sebastien Lecommandoux
Polymers 2016, 8(5), 192;
Received: 26 February 2016 / Revised: 14 April 2016 / Accepted: 3 May 2016 / Published: 14 May 2016
(This article belongs to the Special Issue Polymers for Aqueous Media)
A water-soluble, core-multishell (CMS) nanocarrier based on a new hyperbranched polyester core building block was synthesized and characterized towards drug transport and degradation of the nanocarrier. The hydrophobic drug dexamethasone was encapsulated and the enzyme-mediated biodegradability was investigated by NMR spectroscopy. The new CMS nanocarrier can transport one molecule of dexamethasone and degrades within five days at a skin temperature of 32 °C to biocompatible fragments. View Full-Text
Keywords: nanocarrier; biodegradable; polyester nanocarrier; biodegradable; polyester
Show Figures

Graphical abstract

MDPI and ACS Style

Walker, K.A.; Stumbé, J.-F.; Haag, R. Polyester-Based, Biodegradable Core-Multishell Nanocarriers for the Transport of Hydrophobic Drugs. Polymers 2016, 8, 192.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

Search more from Scilit
Back to TopTop