Next Article in Journal
Self-Assembly of Linear Amphiphilic Pentablock Terpolymer PAAx-PS48-PEO46-PS48-PAAxin Dilute Aqueous Solution
Next Article in Special Issue
Melt- vs. Non-Melt Blending of Complexly Processable Ultra-High Molecular Weight Polyethylene/Cellulose Nanofiber Bionanocomposite
Previous Article in Journal
Fine-Structure Analysis of Perhydropolysilazane-Derived Nano Layers in Deep-Buried Condition Using Polarized Neutron Reflectometry
Previous Article in Special Issue
Design of Experiment Approach to Optimize Hydrophobic Fabric Treatments
Article

The Covalent Tethering of Poly(ethylene glycol) to Nylon 6 Surface via N,N′-Disuccinimidyl Carbonate Conjugation: A New Approach in the Fight against Pathogenic Bacteria

Department of Nanochemistry, Institute for Nanomaterials, Advanced Technologies and Innovation, Technical University of Liberec, Studentská 1402/2, 46117 Liberec 1, Czech Republic
*
Author to whom correspondence should be addressed.
Polymers 2020, 12(10), 2181; https://doi.org/10.3390/polym12102181
Received: 27 August 2020 / Revised: 16 September 2020 / Accepted: 22 September 2020 / Published: 24 September 2020
(This article belongs to the Special Issue Polymer Processing and Surfaces)
Different forms of unmodified and modified Poly(ethylene glycols) (PEGs) are widely used as antifouling and antibacterial agents for biomedical industries and Nylon 6 is one of the polymers used for biomedical textiles. Our recent study focused on an efficient approach to PEG immobilization on a reduced Nylon 6 surface via N,N′–disuccinimidyl carbonate (DSC) conjugation. The conversion of amide functional groups to secondary amines on the Nylon 6 polymer surface was achieved by the reducing agent borane-tetrahydrofuran (BH3–THF) complex, before binding the PEG. Various techniques, including water contact angle and free surface energy measurements, atomic force microscopy, scanning electron microscopy, X-ray photoelectron spectroscopy, and Fourier-transform infrared spectroscopy, were used to confirm the desired surface immobilization. Our findings indicated that PEG may be efficiently tethered to the Nylon 6 surface via DSC, having an enormous future potential for antifouling biomedical materials. The bacterial adhesion performances against S. aureus and P. aeruginosa were examined. In vitro cytocompatibility was successfully tested on pure, reduced, and PEG immobilized samples. View Full-Text
Keywords: poly(ethylene glycol) (PEG); conjugation; N,N′-disuccinimidyl carbonate (DSC); immobilization; surface modification poly(ethylene glycol) (PEG); conjugation; N,N′-disuccinimidyl carbonate (DSC); immobilization; surface modification
Show Figures

Graphical abstract

MDPI and ACS Style

Swar, S.; Máková, V.; Stibor, I. The Covalent Tethering of Poly(ethylene glycol) to Nylon 6 Surface via N,N′-Disuccinimidyl Carbonate Conjugation: A New Approach in the Fight against Pathogenic Bacteria. Polymers 2020, 12, 2181. https://doi.org/10.3390/polym12102181

AMA Style

Swar S, Máková V, Stibor I. The Covalent Tethering of Poly(ethylene glycol) to Nylon 6 Surface via N,N′-Disuccinimidyl Carbonate Conjugation: A New Approach in the Fight against Pathogenic Bacteria. Polymers. 2020; 12(10):2181. https://doi.org/10.3390/polym12102181

Chicago/Turabian Style

Swar, Sumita, Veronika Máková, and Ivan Stibor. 2020. "The Covalent Tethering of Poly(ethylene glycol) to Nylon 6 Surface via N,N′-Disuccinimidyl Carbonate Conjugation: A New Approach in the Fight against Pathogenic Bacteria" Polymers 12, no. 10: 2181. https://doi.org/10.3390/polym12102181

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop