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Open AccessArticle

UV Light Assisted Coating Method of Polyphenol Caffeic Acid and Mediated Immobilization of Metallic Silver Particles for Antibacterial Implant Surface Modification

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Department of Mechanical Design Engineering, Graduate School, Chonbuk National University, Jeonju 54896, Korea
2
Department of Bionanosystem Engineering, Chonbuk National University, Jeonju 54896, Korea
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Division of Mechanical Design Engineering, Chonbuk National University, Jeonju 54896, Korea
*
Authors to whom correspondence should be addressed.
Polymers 2019, 11(7), 1200; https://doi.org/10.3390/polym11071200
Received: 28 May 2019 / Revised: 11 July 2019 / Accepted: 12 July 2019 / Published: 18 July 2019
(This article belongs to the Special Issue Polymer Biointerfaces)
Titanium implants are extensively used in biomedical applications due to their excellent biocompatibility, corrosion resistance, and superb mechanical stability. In this work, we present the use of polycaffeic acid (PCA) to immobilize metallic silver on the surface of titanium materials to prevent implant bacterial infection. Caffeic acid is a plant-derived phenolic compound, rich in catechol moieties and it can form functional coatings using alkaline buffers and with UV irradiation. This combination can trigger oxidative polymerization and deposition on the surface of metallic substrates. Using PCA can also give advantages in bone implants in decreasing inflammation by decelerating macrophage and osteoclast activity. Here, chemical and physical properties were investigated using FE-SEM, EDS, XPS, AFM, and contact angle. The in vitro biocompatibility and antibacterial studies show that PCA with metallic silver can inhibit bacterial growth, and proliferation of MC-3T3 cells was observed. Therefore, our results suggest that the introduced approach can be considered as a potential method for functional implant coating application in the orthopedic field. View Full-Text
Keywords: titanium implants; polycaffeic acid; metallic silver particles; anti-bacterial properties titanium implants; polycaffeic acid; metallic silver particles; anti-bacterial properties
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MDPI and ACS Style

Lee, J.Y.; Aguilar, L.E.; Park, C.H.; Kim, C.S. UV Light Assisted Coating Method of Polyphenol Caffeic Acid and Mediated Immobilization of Metallic Silver Particles for Antibacterial Implant Surface Modification. Polymers 2019, 11, 1200.

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