Next Article in Journal
Fabric Composites Reinforced with Thermally Bonded and Irregularly Aligned Filaments: Preparation and Puncture Resistant Performance
Next Article in Special Issue
TiO2 NPs Assembled into a Carbon Nanofiber Composite Electrode by a One-Step Electrospinning Process for Supercapacitor Applications
Previous Article in Journal
Polyvinylnorbornene Gas Separation Membranes
Previous Article in Special Issue
Electrospun Combination of Peppermint Oil and Copper Sulphate with Conducive Physico-Chemical properties for Wound Dressing Applications
Article Menu
Issue 4 (April) cover image

Export Article

Open AccessArticle

Engineered Electrospun Polyurethane Composite Patch Combined with Bi-functional Components Rendering High Strength for Cardiac Tissue Engineering

1
School of Biomedical Engineering and Health Sciences, Faculty of Engineering, Universiti Teknologi Malaysia, Skudai 81310, Malaysia
2
Department for Management of Science and Technology Development, Ton Duc Thang University, Ho Chi Minh City, Vietnam
3
Faculty of Applied Sciences, Ton Duc Thang University, Ho Chi Minh City, Vietnam
4
IJNUTM Cardiovascular Engineering center, School of Biomedical Engineering and Health Sciences, Faculty of Engineering, Universiti Teknologi Malaysia, Skudai 81310, Malaysia
5
Centre for Artificial Intelligence and Robotics, Universiti Teknologi Malaysia, Kuala Lumpur 54100, Malaysia
6
School of Electrical Engineering, Faculty of Engineering, Universiti Teknologi Malaysia, Johor Bahru 81310, Malaysia
7
Media and Game Innovation Centre of Excellence (MaGICX), Institute of Human Centered Engineering (iHumEn), Universiti Teknologi Malaysia, Skudai 81310, Malaysia
8
School of Computing, Faculty of Engineering, Universiti Teknologi Malaysia, Skudai 81310, Malaysia
*
Author to whom correspondence should be addressed.
Polymers 2019, 11(4), 705; https://doi.org/10.3390/polym11040705
Received: 18 March 2019 / Revised: 5 April 2019 / Accepted: 11 April 2019 / Published: 17 April 2019
(This article belongs to the Special Issue Electrospun Nanofibers: Theory and Its Applications)
  |  
PDF [3829 KB, uploaded 19 April 2019]
  |  

Abstract

Cardiovascular application of nanomaterial’s is of increasing demand and its usage is limited by its mechanical and blood compatible properties. In this work, an attempt is made to develop an electrospun novel nanocomposite loaded with basil oil and titanium dioxide (TiO2) particles. The composite material displayed increase in hydrophobic and reduced fiber diameter compared to the pristine polymer. Fourier transform infrared spectroscopy results showed the interaction of the pristine polymer with the added substances. Thermal analysis showed the increased onset degradation, whereas the mechanical testing portrayed the increased tensile strength of the composites. Finally, the composite delayed the coagulation times and also rendered safe environment for red blood cells signifying its suitability to be used in contact with blood. Strikingly, the cellular toxicity of the developed composite was lower than the pristine polymer suggesting its compatible nature with the surrounding tissues. With these promising characteristics, developed material with enhanced physicochemical properties and blood compatibility can be successfully utilized for cardiac tissue applications. View Full-Text
Keywords: polyurethane; basil/titanium dioxide; physico-chemical properties; biocompatibility; cardiac tissue applications polyurethane; basil/titanium dioxide; physico-chemical properties; biocompatibility; cardiac tissue applications
Figures

Graphical abstract

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
SciFeed

Share & Cite This Article

MDPI and ACS Style

Mani, M.P.; Jaganathan, S.K.; Faudzi, A.A.M.; Sunar, M.S. Engineered Electrospun Polyurethane Composite Patch Combined with Bi-functional Components Rendering High Strength for Cardiac Tissue Engineering. Polymers 2019, 11, 705.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Polymers EISSN 2073-4360 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top