Next Article in Journal
Mechanism of Heat Transfer through Porous Media of Inorganic Intumescent Coating in Cone Calorimeter Testing
Next Article in Special Issue
Helix-Sense-Selective Polymerization of Phenylacetylenes Having a Porphyrin and a Zinc-Porphyrin Group: One-Handed Helical Arrangement of Porphyrin Pendants
Previous Article in Journal
Polymer-Magnetic Composite Particles of Fe3O4/Poly(o-anisidine) and Their Suspension Characteristics under Applied Magnetic Fields
Previous Article in Special Issue
Use of Grafted Voltage Stabilizer to Enhance Dielectric Strength of Cross-Linked Polyethylene
Open AccessArticle

Fabrication and Application of Dual-Modality Polymer Nanoparticles Based on an Aggregation-Induced Emission-Active Fluorescent Molecule and Magnetic Fe3O4

1
School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, China
2
Shanghai Key Laboratory of Magnetic Resonance and Department of Physics, East China Normal University, 3663 North Zhongshan Road, Shanghai 200062, China
*
Author to whom correspondence should be addressed.
Polymers 2019, 11(2), 220; https://doi.org/10.3390/polym11020220
Received: 28 December 2018 / Revised: 23 January 2019 / Accepted: 24 January 2019 / Published: 28 January 2019
(This article belongs to the Special Issue Synthesis and Application of Conjugated Polymers)
Fluorescent magnetic nanoparticles (NPs) utilized for imaging hold great promise for biomedical applications, but it remains a challenging task. Here, we report novel dual-modality NPs using an aggregation-induced emission (AIE)-active and near-infrared (NIR) emissive dye (TPAS) and magnetic Fe3O4 as the core, and biocompatible polymer Pluronic F-127 as the encapsulation matrix by self-assembly procedures. The obtained fluorescent-magnetic AIE NPs have both high fluorescence quantum yield (13.8%) at 700 nm and high magnetic saturation value. With good photostability and biocompatibility, the resulting NPs show effective MRI ability, but also a stain in cytoplasm with a strong NIR fluorescent signal. View Full-Text
Keywords: dual-modality; AIE; MRI; bioimaging dual-modality; AIE; MRI; bioimaging
Show Figures

Graphical abstract

MDPI and ACS Style

Wang, L.; Huang, M.; Tang, H.; Cao, D.; Zhao, Y. Fabrication and Application of Dual-Modality Polymer Nanoparticles Based on an Aggregation-Induced Emission-Active Fluorescent Molecule and Magnetic Fe3O4. Polymers 2019, 11, 220.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop