In-Vitro Hemocompatibility of Polyaniline Functionalized by Bioactive Molecules
Abstract
:1. Introduction
2. Materials and Methods
2.1. Sample Preparation
2.2. Surface Energy Measurement
2.3. Conductivity
2.4. Anticoagulation Test
3. Results and Discussion
4. Conclusions
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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γtot ± SD (mN·m−1) | |||
---|---|---|---|
Day 0 | Day 7 | Day 14 | |
PANI-BSDBS | 51 ± 3 | 51 ± 2 | 50 ± 7 |
PANI-SSDBS | 51 ± 3 | 47 ± 4 | 44 ± 4 |
PANI-BTaurine | 51 ± 7 | 53 ± 2 | 38 ± 12 |
PANI-STaurine | 55 ± 8 | 45 ± 7 | 47 ± 2 |
PANI-BACES | 41 ± 1 | 37 ± 1 | 45 ± 0 |
PANI-MSDBS | 46 ± 5 | 47 ± 4 | 46 ± 4 |
PANI-MTaurine | 53 ± 4 | 44 ± 10 | 46 ± 4 |
PANI-S (a) | 52.54 | n.d. | n.d. |
PANI-B (a) | 50.88 | n.d. | n.d. |
Sample | Day 0 | Day 7 | Day 14 |
---|---|---|---|
PANI-MSDBS | 7.0 ± 0.03 | 5.7 ± 0.002 | 5.2 ± 0.004 |
PANI-MTaurine | 17.9 ± 0.01 | 16.5 ± 0.004 | 15.8 ± 0.003 |
PT [s] | aPPT [s] | TCT [s] | |
---|---|---|---|
Reference | 12.1 ± 0.1 | 25.2 ± 0.5 | 16.7 ± 0.3 |
PANI-BSDBS | 12.2 ± 0.6 | 29.5 ± 4.7 | 20.0 ± 2.2 |
PANI-SSDBS | 11.8 ± 0.2 | 25.6 ± 0.3 | 18.3 ± 0.3 |
PANI-BTaurin | 11.8 ± 0.0 | 25.4 ± 0.5 | 17.7 ± 0.5 |
PANI-STaurin | 11.8 ± 0.2 | 26.9 ± 0.6 | 19.2 ± 0.4 |
PANI-BACES | 12.3 ± 0.0 | 25.4 ± 0.3 | 15.4 ± 0.4 |
PANI-MSDBS | 12.0 ± 0.1 | 25.8 ± 0.6 | 18.2 ± 0.5 |
PANI-MTaurin | 12.1 ± 0.3 | 30.0 ± 2.5 | 19.7 ± 0.6 |
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Skopalová, K.; Capáková, Z.; Bober, P.; Pelková, J.; Stejskal, J.; Kašpárková, V.; Lehocký, M.; Junkar, I.; Mozetič, M.; Humpolíček, P. In-Vitro Hemocompatibility of Polyaniline Functionalized by Bioactive Molecules. Polymers 2019, 11, 1861. https://doi.org/10.3390/polym11111861
Skopalová K, Capáková Z, Bober P, Pelková J, Stejskal J, Kašpárková V, Lehocký M, Junkar I, Mozetič M, Humpolíček P. In-Vitro Hemocompatibility of Polyaniline Functionalized by Bioactive Molecules. Polymers. 2019; 11(11):1861. https://doi.org/10.3390/polym11111861
Chicago/Turabian StyleSkopalová, Kateřina, Zdenka Capáková, Patrycja Bober, Jana Pelková, Jaroslav Stejskal, Věra Kašpárková, Marián Lehocký, Ita Junkar, Miran Mozetič, and Petr Humpolíček. 2019. "In-Vitro Hemocompatibility of Polyaniline Functionalized by Bioactive Molecules" Polymers 11, no. 11: 1861. https://doi.org/10.3390/polym11111861