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Recent Advances in Polymeric Nanocomposites of Metal-Organic Frameworks (MOFs)

by Jun Zhong 1, Ranjith Kumar Kankala 1,2,3,*, Shi-Bin Wang 1,2,3 and Ai-Zheng Chen 1,2,3,*
Institute of Biomaterials and Tissue Engineering, Huaqiao University, Xiamen 361021, China
College of Chemical Engineering Huaqiao University, Xiamen 361021, China
Fujian Provincial Key Laboratory of Biochemical Technology (Huaqiao University), Xiamen 361021, China
Authors to whom correspondence should be addressed.
Polymers 2019, 11(10), 1627;
Received: 21 August 2019 / Revised: 25 September 2019 / Accepted: 3 October 2019 / Published: 9 October 2019
(This article belongs to the Special Issue Polymeric Colloidal Materials for Biomedical Applications)
Recently, metal-organic frameworks (MOFs) have garnered enormous attention from researchers owing to their superior physicochemical properties, which are of particular interest in various fields such as catalysis and the diverse areas of biomedicine. Despite their position in the utilization for various applications compared to other innovative nanocarriers such as dendrimers and mesoporous silica nanoparticles (MSNs), in terms of advantageous physicochemical attributes, as well as attractive textural properties, ease of characterization, and abundant surface chemistry for functionalization and other benefits, MOFs yet suffer from several issues such as poor degradability, which might lead to accumulation-induced biocompatibility risk. In addition, some of the MOFs suffer from a shortcoming of poor colloidal stability in the aqueous solution, hindering their applicability in diverse biomedical fields. To address these limitations, several advancements have been made to fabricate polymeric nanocomposites of MOFs for their utility in various biomedical fields. In this review, we aim to provide a brief emphasis on various organic polymers used for coating over MOFs to improve their physicochemical attributes considering a series of recently reported intriguing studies. Finally, we summarize with perspectives. View Full-Text
Keywords: metal-organic frameworks; porosity; biocompatibility; surface functionalization; bio-interfaces metal-organic frameworks; porosity; biocompatibility; surface functionalization; bio-interfaces
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MDPI and ACS Style

Zhong, J.; Kankala, R.K.; Wang, S.-B.; Chen, A.-Z. Recent Advances in Polymeric Nanocomposites of Metal-Organic Frameworks (MOFs). Polymers 2019, 11, 1627.

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