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Polymers 2018, 10(9), 987; https://doi.org/10.3390/polym10090987

Photo-Crosslinked Keratin/Chitosan Membranes as Potential Wound Dressing Materials

1,2,†
,
2,†
,
2
,
1,* and 2,*
1
Institute of Biotechnology, National Taiwan University, Taipei 10617, Taiwan
2
Department of Chemical Engineering, National Taiwan University, Taipei 10617, Taiwan
These authors contributed equally to this work.
*
Authors to whom correspondence should be addressed.
Received: 29 June 2018 / Revised: 28 August 2018 / Accepted: 28 August 2018 / Published: 4 September 2018
(This article belongs to the Special Issue Protein Biopolymer)
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Abstract

In this study, we combined two kinds of natural polymers, chitosan and keratin, to develop a portable composite membrane via UV irradiation. UV-crosslinking without an additional chemical agent makes the fabrication more ideal by reducing reactants and avoiding residual toxic chemicals. This novel composite could perform synergistic functions benefitting from chitosan and keratin; including a strong mechanical strength, biodegradability, biocompatibility, better cell adhesion, and proliferation characteristics. Furthermore, compared with our previous research, this keratin-chitosan composite membrane was improved in that it was made to be portable, enabling it to be versatile and have various applications in vitro and in vivo. Based on these facts, this innovative composite membrane has high potential for serving as an outstanding candidate for wound healing or other biomedical applications. View Full-Text
Keywords: keratin; chitosan; composite membrane; UV-crosslink keratin; chitosan; composite membrane; UV-crosslink
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Lin, C.-W.; Chen, Y.-K.; Lu, M.; Lou, K.-L.; Yu, J. Photo-Crosslinked Keratin/Chitosan Membranes as Potential Wound Dressing Materials. Polymers 2018, 10, 987.

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