Next Article in Journal
Van Der Waals Heterostructures between Small Organic Molecules and Layered Substrates
Previous Article in Journal
Molecular Structure, Spectroscopic and DFT Computational Studies of Arylidene-1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione
Article Menu

Export Article

Open AccessArticle
Crystals 2016, 6(9), 114;

Synthesis of Novel p-tert-Butylcalix[4]arene Derivative: Structural Characterization of a Methanol Inclusion Compound

Facultad de Ciencias, Universidad de Chile, Las Palmeras 3425, Santiago 7800003, Chile
Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, Sergio Livingstone Pohlhammer 1007 (ex Olivos), Santiago 7800003, Chile
Author to whom correspondence should be addressed.
Academic Editor: Helmut Cölfen
Received: 5 July 2016 / Revised: 26 August 2016 / Accepted: 5 September 2016 / Published: 9 September 2016
(This article belongs to the Section Biomolecular Crystals)
Full-Text   |   PDF [2775 KB, uploaded 9 September 2016]   |  


A p-tertbutylcalix[4]arene derivative was synthesized from a reaction of the diisothiocyanate p-tertbutylcalix[4]arene, obtaining crystals that were then characterized by mass spectroscopy, Raman spectroscopy, and single-crystal X-ray diffraction. The molecule presents two acid carbamothioic-n-ethoxy-methyl-ester substituent groups. Through crystallization of this compound, it was also found that it includes a methanol molecule within the aromatic cavity. The inclusion of the methanol molecule is due to favorable CH∙∙∙π interactions. View Full-Text
Keywords: calix[4]arene; crystal structure; synthesis calix[4]arene; crystal structure; synthesis

Graphical abstract

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Share & Cite This Article

MDPI and ACS Style

Moris, S.; Galdámez, A.; Jara, P.; Saitz-Barria, C. Synthesis of Novel p-tert-Butylcalix[4]arene Derivative: Structural Characterization of a Methanol Inclusion Compound. Crystals 2016, 6, 114.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Crystals EISSN 2073-4352 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top