Kinetic Study of the Herrmann–Beller Palladacycle-Catalyzed Suzuki–Miyaura Coupling of 4-Iodoacetophenone and Phenylboronic Acid
Abstract
:1. Introduction
2. Results
2.1. Experimental Kinetic Study
2.1.1. Preliminary Observations
2.1.2. Temperature Effect and Activation Energy
2.1.3. Effect of the Catalyst Concentration
2.1.4. Effect of the Aryl Halide Concentration
2.1.5. Effect of Base and Phenylboronic Acid Concentrations
2.2. Modeling and Discussion
3. Materials and Methods
4. Conclusions
Supplementary Materials
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
Abbreviations
SM | Suzuki–Miyaura |
ArI | 4-iodoacetophenone |
Concentration of mononuclear palladium | |
Ea | activation energy |
r | rate of product formation (mol/min) |
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Bourouina, A.; Oswald, A.; Lido, V.; Dong, L.; Rataboul, F.; Djakovitch, L.; de Bellefon, C.; Meille, V. Kinetic Study of the Herrmann–Beller Palladacycle-Catalyzed Suzuki–Miyaura Coupling of 4-Iodoacetophenone and Phenylboronic Acid. Catalysts 2020, 10, 989. https://doi.org/10.3390/catal10090989
Bourouina A, Oswald A, Lido V, Dong L, Rataboul F, Djakovitch L, de Bellefon C, Meille V. Kinetic Study of the Herrmann–Beller Palladacycle-Catalyzed Suzuki–Miyaura Coupling of 4-Iodoacetophenone and Phenylboronic Acid. Catalysts. 2020; 10(9):989. https://doi.org/10.3390/catal10090989
Chicago/Turabian StyleBourouina, Amine, Alexis Oswald, Valentin Lido, Lu Dong, Franck Rataboul, Laurent Djakovitch, Claude de Bellefon, and Valérie Meille. 2020. "Kinetic Study of the Herrmann–Beller Palladacycle-Catalyzed Suzuki–Miyaura Coupling of 4-Iodoacetophenone and Phenylboronic Acid" Catalysts 10, no. 9: 989. https://doi.org/10.3390/catal10090989