Acetylenic Carbon-Containing Stable Five-Membered Metallacycles

Round 1

Reviewer 1 Report

The review entitled «acetylenic carbon-containing stable fve-membered metallacycle » by Hu and Li warrants publication in catalysts.

The introducrion allow gaining informations of general interest for a broad audience including graduate students.

Some minor points should be adressed and modified throughout the manuscript before publishing

Line 22. The authors state that the smallest isolated metallacycle of these series is an eight membered ring. I agree, but it should be mentioned that cyclo-heptyne, -hexyne or pentyne do exist as transient reactional intermediates. See Krebs, Adolf; Wilke, Jürgen (1983). "Angle Strained Cycloalkynes". Topics in Current Chemistry. 109: 189–233. doi:10.1007/BFb0018059.

 

Line 81. Please replace property by character or nature

Line 82. C2-C3 as a 2e ligand.It is not clear to me  if the interaction decreases or increases the stability and what is the contribution of the ligand ? please comment on.

Line 105. Substituents

Line 106. Replace « , because… stable » by in agreement with general statements in the introduction.

Line 109. Comment on the role of Ti and Hf ?

Line 150 and 369. I would prefer noteworthy instead of noteworthily

Line 163-164 in scheme 8. Please highlight the zig-zag fragment in complexes.

Line 219. Heading shoul db ein the upper page

Line 270. Should be NaPF6 ?

Line 288. Coinage metals should be replaced by Au, Ag and Cu

Line 294. Brönsted acids

Line 302. Replace primarily by selectively

Line 341. Replace « attacked by » by subjected to addition of

Line364-365 ; confirm structures of compounds 77 and 78 and the presence of OS-H bond.

Line 369. To which compound does the lactone-fused OSpentalyne refer to

Line 389.is there a difference between PF6 and BF4 in this case ? If yes, please precise the role of each

Line 394. Excess of alkynes

Line 402. Cycloaddition products are

Line 403. Were reacted with 55

Line 400. Replace the sentence by « Interestingly, the presence of HBF4 induced the formatio, o two lactone-fused metallapentalynes 87 and 88 accompagi=nied by the migraiton of Os-C bond.

Line 419 – scheme 28. The OS=N double bond is unlikely, please check.

Line 444. Complexes such as the …

Line 449. Resulted in ring opening of the metallacycles

Line 451-453. The sentence is not clear to me. Some part of the sentence missing ?

 

Author Response

Please see the attachment.

Author Response File: Author Response.pdf

Reviewer 2 Report

The current review fills a gap in the chemistry of metallacycles. The paper is well-written and it is easy to follow and understand.

Some minor issues:

• The reaction conditions (such as solvents, temperature etc.) should be shown in the Schemes.
• There are some laballing issue: e.g. Scheme 24 or Scheme 25 the negative charge of the PF6 BF4 etc anions ( only "-" was used and not "- in the circle" 
• The DFT results should be discussed more precisely (at least the method/basis set and the energy values for the calculated reactions and not only writing "DFT calculations suggest"

After the corrections of the above mentioned problems, I am happy to accept the review for publishing in Catalysts.

Author Response

Please see the attachment.

Author Response File: Author Response.pdf

Reviewer 3 Report

The submitted review paper gave a comprehensive compilation of scientific literature dealing with the synthesis, characteristics and transformations of five-membered metallacycles containing of one carbon-carbon triple bond. The paper is well organized, the subject properly presented and related literature comprehensively given. The submitted review paper should be very instructive to readers working on the matter rather than general scientific community related to general organic chemistry. The reviewed matter is not related to any catalytic transformation of catalysts, so that I feel that the submission not follows the aim and scope of Catalysts.

My overall impression on the paper is positive I would strongly support the publication of submitted paper in any journal of organic chemistry, but since the subject of the review doesn´t follow the scope and aim of Catalysts I would suggest the re-submission of the paper to MOlecules.

Author Response

Please see the attachment.

Author Response File: Author Response.pdf

Round 2

Reviewer 3 Report

Ok, if the authors feel that compounds reviewed should have potential characteristics as catalysts in future, than I should share their optimism and conclude that their submission follows the Aim and Scope of the journal Catalysts.