Correction: Ricci et al. Causes of Childhood Cancer: A Review of the Recent Literature: Part I—Childhood Factors. Cancers 2024, 16, 1297
Error in Table
Reference
- Ricci, A.M.; Emeny, R.T.; Bagley, P.J.; Blunt, H.B.; Butow, M.E.; Morgan, A.; Alford-Teaster, J.A.; Titus, L.; Walston, R.R., III; Rees, J.R. Causes of Childhood Cancer: A Review of the Recent Literature: Part I—Childhood Factors. Cancers 2024, 16, 1297. [Google Scholar] [CrossRef] [PubMed]
| Exposure | Notes |
|---|---|
| Strong evidence of association with childhood cancer | |
| Genetics | Germline cancer predisposition genes are strongly associated with an increased risk of multiple childhood cancers. There is also increasing research into the impact of more common genetic variants and epigenetics. |
| Birth defects | Major birth defects and some chromosomal syndromes are strongly associated with an increased risk of multiple childhood cancers. |
| Prior cancer and cancer treatments | Childhood cancer treatment is associated with a significant risk of developing a subsequent primary cancer. |
| Medical ionizing radiation | There is a strong link between CT scans in childhood and an increased risk of childhood cancer, particularly leukemia and brain cancer. |
| Ultraviolet light | Exposure to UV light in childhood is associated with a significant risk of melanoma in later life. Public health interventions to reduce indoor tanning by minors is associated with decreased cancer incidence. |
| Organ transplantation | Immunosuppression after solid organ transplant is associated with a significantly increased risk for several childhood cancers. |
| Vaccinations | Vaccination against certain carcinogenic viruses is strongly associated with a decreased childhood cancer risk. There is more limited evidence that childhood vaccinations (against non-carcinogenic viruses) more broadly may decrease cancer risk. |
| Infections | Certain carcinogenic viruses (e.g., Epstein–Barr virus) are strongly associated with childhood cancer. There is limited evidence that exposure to common childhood infections may decrease childhood cancer risk. |
| Diet and breastfeeding | Breastfeeding is associated with a lower risk of leukemia, and possibly rhabdomyosarcoma, but evidence is lacking for other cancer types. There was some evidence for decreased leukemia risk associated with improved diet quality and a higher cancer risk associated with lower diet quality. |
| Mixed evidence of association with childhood cancer | |
| Allergies | Rhabdomyosarcoma is less common in children with allergies, but the evidence on associations between allergies and other childhood cancer risk is mixed. |
| Weak or no evidence of association with childhood cancer | |
| Medications in childhood | Human growth hormone was not associated with a significantly increased risk of a first childhood cancer, although the risk may be different when used in childhood cancer survivors. Studies evaluating immunomodulatory agents and childhood cancer risk have been methodologically challenged and while it seems underlying inflammatory conditions may be associated with an increased risk for childhood cancer, the role of medications is not clearly established. |
| Body mass index | There was too little research to draw conclusions on the impact of childhood obesity on childhood cancer risk. |
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© 2026 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.
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Ricci, A.M.; Emeny, R.T.; Bagley, P.J.; Blunt, H.B.; Butow, M.E.; Morgan, A.; Alford-Teaster, J.A.; Titus, L.; Walston, R.R., III; Rees, J.R. Correction: Ricci et al. Causes of Childhood Cancer: A Review of the Recent Literature: Part I—Childhood Factors. Cancers 2024, 16, 1297. Cancers 2026, 18, 1231. https://doi.org/10.3390/cancers18081231
Ricci AM, Emeny RT, Bagley PJ, Blunt HB, Butow ME, Morgan A, Alford-Teaster JA, Titus L, Walston RR III, Rees JR. Correction: Ricci et al. Causes of Childhood Cancer: A Review of the Recent Literature: Part I—Childhood Factors. Cancers 2024, 16, 1297. Cancers. 2026; 18(8):1231. https://doi.org/10.3390/cancers18081231
Chicago/Turabian StyleRicci, Angela M., Rebecca T. Emeny, Pamela J. Bagley, Heather B. Blunt, Mary E. Butow, Alexandra Morgan, Jennifer A. Alford-Teaster, Linda Titus, Raymond R. Walston, III, and Judy R. Rees. 2026. "Correction: Ricci et al. Causes of Childhood Cancer: A Review of the Recent Literature: Part I—Childhood Factors. Cancers 2024, 16, 1297" Cancers 18, no. 8: 1231. https://doi.org/10.3390/cancers18081231
APA StyleRicci, A. M., Emeny, R. T., Bagley, P. J., Blunt, H. B., Butow, M. E., Morgan, A., Alford-Teaster, J. A., Titus, L., Walston, R. R., III, & Rees, J. R. (2026). Correction: Ricci et al. Causes of Childhood Cancer: A Review of the Recent Literature: Part I—Childhood Factors. Cancers 2024, 16, 1297. Cancers, 18(8), 1231. https://doi.org/10.3390/cancers18081231

