Gender Differences in Sinonasal Cancer Incidence: Data from the Italian Registry
Abstract
:Simple Summary
Abstract
1. Introduction
2. Materials and Methods
3. Results
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Variable | Men N (%) | Women N (%) |
---|---|---|
Sex | 2073 (73) | 778 (27) |
Age, years (mean ± SD) | 67 ± 12.4 | 66.0 ± 15.2 |
Age class | ||
0–44 | 104 (5) | 82 (11) |
45–54 | 230 (11) | 92 (12) |
0–54 | 334 (16) | 174 (22) |
55–64 | 460 (22) | 142 (18) |
65–74 | 639 (31) | 195 (25) |
75+ | 640 (31) | 267 (34) |
55+ | 1739 (84) | 604 (78) |
Topography (ICD-X codes) | ||
Nasal cavities (C30.0) | 1204 (50) | 452 (50) |
Maxillary sinus (C31.0) | 420 (17) | 220 (24) |
Ethmoidal sinus (C31.1) | 583 (24) | 146 (16) |
Frontal sinus (C31.2) | 48 (2) | 14 (2) |
Sphenoidal sinus (C31.3) | 113 (5) | 51 (6) |
Overlapping lesion of accessory sinuses (C31.8) | 19 (1) | 8 (1) |
Accessory sinus, unspecified (31.9) | 32 (1) | 10 (1) |
Histology (a) | ||
Adenocarcinomas | ||
ITAC | 678 (33) | 74 (10) |
Non-ITAC | 93 (5) | 42 (6) |
AD NOS | 160 (8) | 26 (3) |
SGC | 112 (6) | 108 (14) |
Squamous cell carcinomas | ||
SCC | 730 (36) | 376 (50) |
Neuroendocrine carcinomas | ||
NEC | 43 (2) | 21 (3) |
Other epithelial neoplasms | ||
SNC NOS | 108 (5) | 49 (6) |
SNUC | 114 (6) | 57 (8) |
Malignant Neoplasm | 16 (1) | 9 (1) |
Variable | Incidence Rate | IRR (95% CI) | |
---|---|---|---|
Men | Women | ||
Age-class | |||
0–24 | - | - | - |
25–34 | 0.01 | 0.01 | 0.98 (0.28–3.37) |
35–44 | 0.04 | 0.03 | 1.22 (0.70–2.12) |
45–54 | 0.09 | 0.03 | 2.83 (1.82–4.39) |
55–64 | 0.15 | 0.04 | 3.55 (2.44–5.19) |
65–74 | 0.22 | 0.06 | 3.42 (2.54–4.62) |
75+ | 0.26 | 0.06 | 4.05 (3.11–5.27) |
Topography (most represented) | |||
Nasal cavities (C30.0) | 0.51 | 0.15 | 3.41 (2.82–4.13) |
Maxillary sinus (C31.0) | 0.16 | 0.06 | 2.47 (1.82–3.35) |
Ethmoid sinus (C31.1) | 0.18 | 0.04 | 4.01 (2.86–5.63) |
Histology (main groups) | |||
Adenocarcinoma | 0.35 | 0.07 | 5.00 (3.83–6.53) |
Squamous cell carcinoma | 0.30 | 0.13 | 2.31 (1.85–2.88) |
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Binazzi, A.; di Marzio, D.; Mensi, C.; Consonni, D.; Miligi, L.; Piro, S.; Zajacovà, J.; Sorasio, D.; Galli, P.; Camagni, A.; et al. Gender Differences in Sinonasal Cancer Incidence: Data from the Italian Registry. Cancers 2024, 16, 2053. https://doi.org/10.3390/cancers16112053
Binazzi A, di Marzio D, Mensi C, Consonni D, Miligi L, Piro S, Zajacovà J, Sorasio D, Galli P, Camagni A, et al. Gender Differences in Sinonasal Cancer Incidence: Data from the Italian Registry. Cancers. 2024; 16(11):2053. https://doi.org/10.3390/cancers16112053
Chicago/Turabian StyleBinazzi, Alessandra, Davide di Marzio, Carolina Mensi, Dario Consonni, Lucia Miligi, Sara Piro, Jana Zajacovà, Denise Sorasio, Paolo Galli, Angela Camagni, and et al. 2024. "Gender Differences in Sinonasal Cancer Incidence: Data from the Italian Registry" Cancers 16, no. 11: 2053. https://doi.org/10.3390/cancers16112053
APA StyleBinazzi, A., di Marzio, D., Mensi, C., Consonni, D., Miligi, L., Piro, S., Zajacovà, J., Sorasio, D., Galli, P., Camagni, A., Calisti, R., Massacesi, S., Cozzi, I., Balestri, A., Murano, S., Fedeli, U., Comiati, V., Eccher, S., Lattanzio, S., ... ReNaTuNS Working Group. (2024). Gender Differences in Sinonasal Cancer Incidence: Data from the Italian Registry. Cancers, 16(11), 2053. https://doi.org/10.3390/cancers16112053