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Open AccessReview

Clinical Decision Support Systems in Breast Cancer: A Systematic Review

UCD School of Computer Science, University College Dublin, Dublin 4, Ireland
CeADAR: Centre for Applied Data Analytics Research, Dublin 4, Ireland
OncoMark Limited, Dublin 4, Ireland
UCD School of Biomolecular and Biomedical Science, UCD Conway Institute, University College Dublin, Dublin 4, Ireland
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Cancers 2020, 12(2), 369;
Received: 31 December 2019 / Revised: 29 January 2020 / Accepted: 31 January 2020 / Published: 6 February 2020
(This article belongs to the Special Issue 3rd Etnean Occupational Medicine Workshop—Breast Cancer and Work)
Breast cancer is the most frequently diagnosed cancer in women, with more than 2.1 million new diagnoses worldwide every year. Personalised treatment is critical to optimising outcomes for patients with breast cancer. A major advance in medical practice is the incorporation of Clinical Decision Support Systems (CDSSs) to assist and support healthcare staff in clinical decision-making, thus improving the quality of decisions and overall patient care whilst minimising costs. The usage and availability of CDSSs in breast cancer care in healthcare settings is increasing. However, there may be differences in how particular CDSSs are developed, the information they include, the decisions they recommend, and how they are used in practice. This systematic review examines various CDSSs to determine their availability, intended use, medical characteristics, and expected outputs concerning breast cancer therapeutic decisions, an area that is known to have varying degrees of subjectivity in clinical practice. Utilising the methodology of Kitchenham and Charter, a systematic search of the literature was performed in Springer, Science Direct, Google Scholar, PubMed, ACM, IEEE, and Scopus. An overview of CDSS which supports decision-making in breast cancer treatment is provided along with a critical appraisal of their benefits, limitations, and opportunities for improvement. View Full-Text
Keywords: breast cancer; clinical decision support system (CDSS); decision support system (DSS); systematic review; breast cancer treatment breast cancer; clinical decision support system (CDSS); decision support system (DSS); systematic review; breast cancer treatment
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Mazo, C.; Kearns, C.; Mooney, C.; Gallagher, W.M. Clinical Decision Support Systems in Breast Cancer: A Systematic Review. Cancers 2020, 12, 369.

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