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Radiomics and Texture Analysis in Laryngeal Cancer. Looking for New Frontiers in Precision Medicine through Imaging Analysis

Otorhinolaryngology-Head & Neck Surgery Department, Hospital Universitario Donostia, 20014 San Sebastian-Donostia, Spain
Biodonostia Health Research Institute, 20014 San Sebastian-Donostia, Spain
Head & Neck Study Group of Young-Otolaryngologists of the International Federations of Oto-rhino-laryngological Societies (YO-IFOS), 13005 Marseille, France
Computational Intelligence Group, Facultad de Informatica UPV/EHU, 20018 San Sebastian-Donostia, Spain
Author to whom correspondence should be addressed.
Cancers 2019, 11(10), 1409;
Received: 28 July 2019 / Revised: 17 September 2019 / Accepted: 17 September 2019 / Published: 20 September 2019
(This article belongs to the Special Issue Emerging Concepts in Treatment of Laryngeal Cancer)
Radiomics and texture analysis represent a new option in our biomarkers arsenal. These techniques extract a large number of quantitative features, analyzing their properties to incorporate them in clinical decision-making. Laryngeal cancer represents one of the most frequent cancers in the head and neck area. We hypothesized that radiomics features can be included as a laryngeal cancer precision medicine tool, as it is able to non-invasively characterize the overall tumor accounting for heterogeneity, being a prognostic and/or predictive biomarker derived from routine, standard of care, imaging data, and providing support during the follow up of the patient, in some cases avoiding the need for biopsies. The larynx represents a unique diagnostic and therapeutic challenge for clinicians due to its complex tridimensional anatomical structure. Its complex regional and functional anatomy makes it necessary to enhance our diagnostic tools in order to improve decision-making protocols, aimed at better survival and functional results. For this reason, this technique can be an option for monitoring the evolution of the disease, especially in surgical and non-surgical organ preservation treatments. This concise review article will explain basic concepts about radiomics and discuss recent progress and results related to laryngeal cancer. View Full-Text
Keywords: larynx; cancer; radiomics; texture analysis larynx; cancer; radiomics; texture analysis
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Chiesa-Estomba, C.M.; Echaniz, O.; Larruscain, E.; Gonzalez-Garcia, J.A.; Sistiaga-Suarez, J.A.; Graña, M. Radiomics and Texture Analysis in Laryngeal Cancer. Looking for New Frontiers in Precision Medicine through Imaging Analysis. Cancers 2019, 11, 1409.

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