Deterministic Lateral Displacement (DLD) Analysis Tool Utilizing Machine Learning towards High-Throughput Separation
Abstract
:1. Introduction
2. Materials and Methods
2.1. Device Design and Experimental Methods
2.2. Program General Information
2.3. Machine Vision—Particle Detection
2.3.1. Automatic Frame Rotation
2.3.2. Automatic Outlet Channel Detection
2.3.3. Outlet Channel Wall Detection
2.3.4. Particle Detection
2.4. Machine Learning—DLD Mode Prediction
3. Results and Discussion
3.1. Machine Vision—Particle Detection
3.2. Machine Learning—DLD Mode Prediction
4. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
Abbreviations
DLD | Deterministic lateral displacement |
CNB | Complement naïve Bayes |
KNN | K-nearest neighbors |
SVM RBF | Support vector machines radial basis function |
OpenCV | Open source computer vision library |
PIMS | Python image sequence |
Re | Reynolds number |
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Outlet #\Run | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 1 | 1 | 1 | |||||||||
2 | 14 | 3 | 6 | 4 | ||||||||
3 | 6 | 1 | 2 | 14 | 7 | |||||||
4 | 4 | 9 | 6 | 2 | 53 | 36 | 6 | |||||
5 | 23 | 14 | 9 | 10 | 9 | 41 | 10 | 8 | ||||
6 | 13 | 5 | 3 | 4 | 1 | 14 | 10 | 7 | ||||
7 | 3 | 11 | 11 | 6 | 10 | 2 | 30 | 8 | 6 | |||
8 | 3 | 17 | 13 | 1 | 6 | 1 | 3 | 3 | 24 | 12 | 5 | |
9 | 4 | 16 | 4 | 1 | 1 | 5 | 14 | 6 | 5 | |||
10 | 5 | 17 | 10 | 1 | 8 | 16 | 4 | 3 | 1 | |||
11 | 7 | 7 | 2 | 1 | 7 | 1 | ||||||
12 | 9 | 2 | 1 | 3 | 3 | 1 | 1 | |||||
Total | 25 | 32 | 94 | 52 | 35 | 53 | 20 | 20 | 43 | 179 | 105 | 45 |
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Gioe, E.; Uddin, M.R.; Kim, J.-H.; Chen, X. Deterministic Lateral Displacement (DLD) Analysis Tool Utilizing Machine Learning towards High-Throughput Separation. Micromachines 2022, 13, 661. https://doi.org/10.3390/mi13050661
Gioe E, Uddin MR, Kim J-H, Chen X. Deterministic Lateral Displacement (DLD) Analysis Tool Utilizing Machine Learning towards High-Throughput Separation. Micromachines. 2022; 13(5):661. https://doi.org/10.3390/mi13050661
Chicago/Turabian StyleGioe, Eric, Mohammed Raihan Uddin, Jong-Hoon Kim, and Xiaolin Chen. 2022. "Deterministic Lateral Displacement (DLD) Analysis Tool Utilizing Machine Learning towards High-Throughput Separation" Micromachines 13, no. 5: 661. https://doi.org/10.3390/mi13050661