CFD Simulations of Microreactors for the Hydrolysis of Cellobiose to Glucose by β-Glucosidase Enzyme
Abstract
:1. Introduction
2. Model Description
3. Results and Discussion
3.1. Effect of Temperature
3.2. Effect of Enzyme Immobilization Yield
3.3. Effect of Mixture Inlet Velocity
4. Conclusions
- The temperature of the reaction;
- The catalyst loading by evaluating the SF factor;
- The mixture inlet velocity.
Author Contributions
Funding
Conflicts of Interest
References
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ΔHi, kJ/mol | νi | c, mol/m3 | cp, (kJ/(kg*K) | ρ, kg/m3 | |
---|---|---|---|---|---|
Cellobiose | −5401.50 | −1 | 4.67 | ||
Water | −285.85 | −1 | |||
Glucose | −1273.30 | 2 | |||
Mixture | 4.186 | 1000 |
Species | Stoichiometric Coefficients | Rate Exponent |
---|---|---|
Cellobiose | 1 | 1 |
H2O | 1 | 0 |
Glucose | 2 | 0 |
Mesh Parameters | Number |
---|---|
Cells | 12,006 |
Faces | 30,029 |
Nodes | 12,692 |
Partitions | 1 |
Parameter | Value |
---|---|
Mixture inlet temperature, Tin (K) | 323–343 |
Mixture inlet velocity, uin (m s−1) | 0.13; 0.013; 1.3 × 10−3; 1.3 × 10−5 |
Inlet C12H22O11 molar fraction | 8.4 × 10−5 |
Surface area washcoat factor | 0.0375–0.075–0.15–0.5 |
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Venezia, V.; Califano, V.; Pota, G.; Costantini, A.; Landi, G.; Di Benedetto, A. CFD Simulations of Microreactors for the Hydrolysis of Cellobiose to Glucose by β-Glucosidase Enzyme. Micromachines 2020, 11, 790. https://doi.org/10.3390/mi11090790
Venezia V, Califano V, Pota G, Costantini A, Landi G, Di Benedetto A. CFD Simulations of Microreactors for the Hydrolysis of Cellobiose to Glucose by β-Glucosidase Enzyme. Micromachines. 2020; 11(9):790. https://doi.org/10.3390/mi11090790
Chicago/Turabian StyleVenezia, Virginia, Valeria Califano, Giulio Pota, Aniello Costantini, Gianluca Landi, and Almerinda Di Benedetto. 2020. "CFD Simulations of Microreactors for the Hydrolysis of Cellobiose to Glucose by β-Glucosidase Enzyme" Micromachines 11, no. 9: 790. https://doi.org/10.3390/mi11090790