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Review

Electrochemical Biosensors for Determination of Colorectal Tumor Biomarkers

1
Max Planck Tandem Group in Nanobioengineering, University of Antioquia, Complejo Ruta N, Calle 67 No. 52-20, Medellín 050010, Colombia
2
Grupo Impacto de los Componentes Alimentarios en la Salud, School of Dietetics and Human Nutrition, University of Antioquia, A.A. 1226, Medellín 050010, Colombia
*
Author to whom correspondence should be addressed.
Micromachines 2020, 11(4), 411; https://doi.org/10.3390/mi11040411
Received: 28 February 2020 / Revised: 13 March 2020 / Accepted: 17 March 2020 / Published: 14 April 2020
(This article belongs to the Special Issue Electrochemical (Bio)sensors for Detection of Clinical Markers)
The accurate determination of specific tumor markers associated with cancer with non-invasive or minimally invasive procedures is the most promising approach to improve the long-term survival of cancer patients and fight against the high incidence and mortality of this disease. Quantification of biomarkers at different stages of the disease can lead to an appropriate and instantaneous therapeutic action. In this context, the determination of biomarkers by electrochemical biosensors is at the forefront of cancer diagnosis research because of their unique features such as their versatility, fast response, accurate quantification, and amenability for multiplexing and miniaturization. In this review, after briefly discussing the relevant aspects and current challenges in the determination of colorectal tumor markers, it will critically summarize the development of electrochemical biosensors to date to this aim, highlighting the enormous potential of these devices to be incorporated into the clinical practice. Finally, it will focus on the remaining challenges and opportunities to bring electrochemical biosensors to the point-of-care testing. View Full-Text
Keywords: colorectal cancer; electrochemical biosensors; biomarkers; in vitro diagnostic; point-of-care testing colorectal cancer; electrochemical biosensors; biomarkers; in vitro diagnostic; point-of-care testing
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MDPI and ACS Style

Quinchia, J.; Echeverri, D.; Cruz-Pacheco, A.F.; Maldonado, M.E.; Orozco, J. Electrochemical Biosensors for Determination of Colorectal Tumor Biomarkers. Micromachines 2020, 11, 411. https://doi.org/10.3390/mi11040411

AMA Style

Quinchia J, Echeverri D, Cruz-Pacheco AF, Maldonado ME, Orozco J. Electrochemical Biosensors for Determination of Colorectal Tumor Biomarkers. Micromachines. 2020; 11(4):411. https://doi.org/10.3390/mi11040411

Chicago/Turabian Style

Quinchia, Jennifer, Danilo Echeverri, Andrés F. Cruz-Pacheco, María E. Maldonado, and Jahir Orozco. 2020. "Electrochemical Biosensors for Determination of Colorectal Tumor Biomarkers" Micromachines 11, no. 4: 411. https://doi.org/10.3390/mi11040411

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