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Application and Technique of Liquid Crystal-Based Biosensors

1
School of Applied Chemistry and Biotechnology, Shenzhen Polytechnic, Shenzhen 518055, China
2
School of Dentistry, University of Detroit Mercy , Detroit, MI 48208, USA
*
Author to whom correspondence should be addressed.
Micromachines 2020, 11(2), 176; https://doi.org/10.3390/mi11020176
Received: 20 November 2019 / Revised: 19 January 2020 / Accepted: 21 January 2020 / Published: 8 February 2020
(This article belongs to the Special Issue Highly Sensitive Transducers for Biosensing)
Liquid crystal biosensors are based on changes in the orientation of liquid crystal molecules induced by specific bonding events of biomolecules. These biosensors are expected to serve as a promising system to detect biomolecules, biomolecular activity, and even small chemical molecules because they are inexpensive, sensitive, simple, effective, and portable. Herein, we introduce the principle and fabrication of liquid crystal biosensors and review the research progress in signal-amplified technology for liquid crystal sensing and its application in the detection of viruses, bacteria, proteins, nucleic acids, and small chemical molecules. In addition, the current theoretical and practical issues related to liquid crystal biosensors were investigated.
Keywords: liquid crystal biosensor; signal amplification technique; liquid crystal cell; virus; bacteria; protein; nucleic acid; small chemical molecules; metal ions liquid crystal biosensor; signal amplification technique; liquid crystal cell; virus; bacteria; protein; nucleic acid; small chemical molecules; metal ions
MDPI and ACS Style

Luan, C.; Luan, H.; Luo, D. Application and Technique of Liquid Crystal-Based Biosensors. Micromachines 2020, 11, 176.

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