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Open AccessArticle

Accelerated Particle Separation in a DLD Device at Re > 1 Investigated by Means of µPIV

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Institute for Microtechology, TU Braunschweig, 38124 Braunschweig, Germany
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Center of Pharmaceutical Engineering (PVZ), TU Braunschweig, 38106 Braunschweig, Germany
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Institute for Particle Technology, TU Braunschweig, 38104 Braunschweig, Germany
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Institute for Fluid Mechanics and Aerodynamics, TU Darmstadt, 64287 Darmstadt, Germany
*
Author to whom correspondence should be addressed.
Micromachines 2019, 10(11), 768; https://doi.org/10.3390/mi10110768
Received: 24 September 2019 / Revised: 8 November 2019 / Accepted: 9 November 2019 / Published: 11 November 2019
(This article belongs to the Special Issue Particles Separation in Microfluidic Devices)
A pressure resistant and optically accessible deterministic lateral displacement (DLD) device was designed and microfabricated from silicon and glass for high-throughput fractionation of particles between 3.0 and 7.0 µm comprising array segments of varying tilt angles with a post size of 5 µm. The design was supported by computational fluid dynamic (CFD) simulations using OpenFOAM software. Simulations indicated a change in the critical particle diameter for fractionation at higher Reynolds numbers. This was experimentally confirmed by microparticle image velocimetry (µPIV) in the DLD device with tracer particles of 0.86 µm. At Reynolds numbers above 8 an asymmetric flow field pattern between posts could be observed. Furthermore, the new DLD device allowed successful fractionation of 2 µm and 5 µm fluorescent polystyrene particles at Re = 0.5–25. View Full-Text
Keywords: microfluidics; deterministic lateral displacement; Reynolds number; particle image velocimetry; size-dependent fractionation microfluidics; deterministic lateral displacement; Reynolds number; particle image velocimetry; size-dependent fractionation
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Kottmeier, J.; Wullenweber, M.; Blahout, S.; Hussong, J.; Kampen, I.; Kwade, A.; Dietzel, A. Accelerated Particle Separation in a DLD Device at Re > 1 Investigated by Means of µPIV. Micromachines 2019, 10, 768.

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