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Magneto-Elastic μ-Vibrator for Smashing Thrombus

1,2, 1 and 1,2,*
1
State Key Lab of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai 200050, China
2
University of Chinese Academy of Sciences, Beijing 100049, China
*
Author to whom correspondence should be addressed.
Micromachines 2019, 10(1), 74; https://doi.org/10.3390/mi10010074
Received: 17 December 2018 / Revised: 13 January 2019 / Accepted: 18 January 2019 / Published: 21 January 2019
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Abstract

A miniaturized thrombus dredger is proposed and developed in this study. The flexural resonance of the µ-resonator dredger is driven by a bulk-extensional magneto-elastic vibrator that is externally excited by alternating magnetic-field. With the fabricated prototype of the resonant dredger, a mice thrombus blocked in a simulated vessel is broken into micro-pieces, and the previously blocked vessel can recover to an unobstructed state within 1 h. A flow-rate ratio detection method is used to evaluate the thrombus-cleaning effectiveness. The comparison between the finite-element simulation and the experimental results validates the flow-rate ratio detection method. By optimally exciting the resonant dredger in its third resonant mode, the flow-rate ratio in the cleaned vessel increases by about 2.7 times compared with that in the partly blocked vessel, and the thrombus is smashed into micro-pieces. View Full-Text
Keywords: micromechanical resonator; biomedical actuator; magneto-elasticity; thrombus clean-up micromechanical resonator; biomedical actuator; magneto-elasticity; thrombus clean-up
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Li, W.; Xue, C.; Li, X. Magneto-Elastic μ-Vibrator for Smashing Thrombus. Micromachines 2019, 10, 74.

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