Next Article in Journal
Cells Deficient in the Fanconi Anemia Protein FANCD2 are Hypersensitive to the Cytotoxicity and DNA Damage Induced by Coffee and Caffeic Acid
Next Article in Special Issue
A Tricky Trait: Applying the Fruits of the “Function Debate” in the Philosophy of Biology to the “Venom Debate” in the Science of Toxinology
Previous Article in Journal
Distribution and Metabolism of Bt-Cry1Ac Toxin in Tissues and Organs of the Cotton Bollworm, Helicoverpa armigera
Previous Article in Special Issue
Tempo and Mode of the Evolution of Venom and Poison in Tetrapods
Open AccessArticle

Canopy Venom: Proteomic Comparison among New World Arboreal Pit-Viper Venoms

1
Venom Evolution Lab, School of Biological Sciences, University of Queensland, St Lucia, QLD 4072, Australia
2
Department of Earth and Biological Sciences, Loma Linda University, Loma Linda, CA 92350, USA
3
Department of Biochemistry & Molecular Biology, Biomedical Discovery Institute, Monash University, Clayton, VIC 3800, Australia
4
School of Chemistry and Molecular Biosciences, University of Queensland, St Lucia, QLD 4072, Australia
5
Baker IDI Heart and Diabetes Institute, 75 Commercial Road, Melbourne, Victoria 3004, Australia
6
Department of Physiology, Biomedical Discovery Institute, Monash University, Clayton, VIC 3800, Australia
7
Aquatic Animal Health, School of Biological Sciences, University of Queensland, St Lucia, QLD 4072 Australia
8
Institute for Molecular Bioscience, University of Queensland, St Lucia, QLD 4072, Australia
9
HEJ Research Institute of Chemistry, ICCBS, University of Karachi, Karachi-75270, Pakistan
*
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Academic Editor: Ronald A. Jenner
Toxins 2016, 8(7), 210; https://doi.org/10.3390/toxins8070210
Received: 22 August 2015 / Revised: 28 May 2016 / Accepted: 16 June 2016 / Published: 8 July 2016
(This article belongs to the Collection Evolution of Venom Systems)
Central and South American pitvipers, belonging to the genera Bothrops and Bothriechis, have independently evolved arboreal tendencies. Little is known regarding the composition and activity of their venoms. In order to close this knowledge gap, venom proteomics and toxin activity of species of Bothriechis, and Bothrops (including Bothriopsis) were investigated through established analytical methods. A combination of proteomics and bioactivity techniques was used to demonstrate a similar diversification of venom composition between large and small species within Bothriechis and Bothriopsis. Increasing our understanding of the evolution of complex venom cocktails may facilitate future biodiscoveries. View Full-Text
Keywords: venom; evolution; pit-viper; enzyme venom; evolution; pit-viper; enzyme
Show Figures

Figure 1

MDPI and ACS Style

Debono, J.; Cochran, C.; Kuruppu, S.; Nouwens, A.; Rajapakse, N.W.; Kawasaki, M.; Wood, K.; Dobson, J.; Baumann, K.; Jouiaei, M.; Jackson, T.N.W.; Koludarov, I.; Low, D.; Ali, S.A.; Smith, A.I.; Barnes, A.; Fry, B.G. Canopy Venom: Proteomic Comparison among New World Arboreal Pit-Viper Venoms. Toxins 2016, 8, 210. https://doi.org/10.3390/toxins8070210

AMA Style

Debono J, Cochran C, Kuruppu S, Nouwens A, Rajapakse NW, Kawasaki M, Wood K, Dobson J, Baumann K, Jouiaei M, Jackson TNW, Koludarov I, Low D, Ali SA, Smith AI, Barnes A, Fry BG. Canopy Venom: Proteomic Comparison among New World Arboreal Pit-Viper Venoms. Toxins. 2016; 8(7):210. https://doi.org/10.3390/toxins8070210

Chicago/Turabian Style

Debono, Jordan; Cochran, Chip; Kuruppu, Sanjaya; Nouwens, Amanda; Rajapakse, Niwanthi W.; Kawasaki, Minami; Wood, Kelly; Dobson, James; Baumann, Kate; Jouiaei, Mahdokht; Jackson, Timothy N.W.; Koludarov, Ivan; Low, Dolyce; Ali, Syed A.; Smith, A. I.; Barnes, Andrew; Fry, Bryan G. 2016. "Canopy Venom: Proteomic Comparison among New World Arboreal Pit-Viper Venoms" Toxins 8, no. 7: 210. https://doi.org/10.3390/toxins8070210

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop