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Volume 13
Issue 11
10.3390/toxins13110810
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Review

Cosmetic Applications of Bee Venom

by
Aida A. Abd El-Wahed
1,
Shaden A. M. Khalifa
2,*,
Mohamed H. Elashal
3,
Syed G. Musharraf
4,
Aamer Saeed
5,
Alfi Khatib
6,7,
Haroon Elrasheid Tahir
8,
Xiaobo Zou
8,
Yahya Al Naggar
9,10,
Arshad Mehmood
11,
Kai Wang
12,* and
Hesham R. El-Seedi
3,13,14,*
1
Department of Bee Research, Plant Protection Research Institute, Agricultural Research Centre, Giza 12627, Egypt
2
Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, S-106 91 Stockholm, Sweden
3
Department of Chemistry, Faculty of Science, Menoufia University, Shebin El-Kom 32512, Egypt
4
H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan
5
Department of Chemistry, Quaid-i-Azam University, Islamabad 45320, Pakistan
6
Pharmacognosy Research Group, Department of Pharmaceutical Chemistry, Kulliyyah of Pharmacy, International Islamic University Malaysia, Kuantan 25200, Pahang Darul Makmur, Malaysia
7
Faculty of Pharmacy, Airlangga University, Surabaya 60155, Indonesia
8
School of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China
9
General Zoology, Institute for Biology, Martin Luther University Halle-Wittenberg, Hoher Weg 8, 06120 Halle, Germany
10
Zoology Department, Faculty of Science, Tanta University, Tanta 31527, Egypt
11
Beijing Engineering and Technology Research Center of Food Additives, Beijing Technology and Business University, Beijing 100048, China
12
Institute of Apicultural Research, Chinese Academy of Agricultural Sciences, Beijing 100093, China
13
Pharmacognosy Group, Department of Pharmaceutical Biosciences, Uppsala University, Biomedical Centre, Box 591, SE-751 24 Uppsala, Sweden
14
International Research Center for Food Nutrition and Safety, Jiangsu University, Zhenjiang 212013, China
 
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Authors to whom correspondence should be addressed.
Toxins 2021, 13(11), 810; https://doi.org/10.3390/toxins13110810
Submission received: 24 September 2021 / Revised: 7 November 2021 / Accepted: 10 November 2021 / Published: 18 November 2021
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Abstract

Bee venom (BV) is a typical toxin secreted by stingers of honeybee workers. BV and BV therapy have long been attractive to different cultures, with extensive studies during recent decades. Nowadays, BV is applied to combat several skin diseases, such as atopic dermatitis, acne vulgaris, alopecia, vitiligo, and psoriasis. BV is used extensively in topical preparations as cosmetics and used as dressing for wound healing, as well as in facemasks. Nevertheless, the safety of BV as a therapeutic choice has always been a concern due to the immune system reaction in some people due to BV use. The documented unfavorable impact is explained by the fact that the skin reactions to BV might expand to excessive immunological responses, including anaphylaxis, that typically resolve over numerous days. This review aims to address bee venom therapeutic uses in skin cosmetics.
Keywords: bee venom; cosmetics applications; skin diseases bee venom; cosmetics applications; skin diseases

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MDPI and ACS Style

El-Wahed, A.A.A.; Khalifa, S.A.M.; Elashal, M.H.; Musharraf, S.G.; Saeed, A.; Khatib, A.; Tahir, H.E.; Zou, X.; Naggar, Y.A.; Mehmood, A.; et al. Cosmetic Applications of Bee Venom. Toxins 2021, 13, 810. https://doi.org/10.3390/toxins13110810

AMA Style

El-Wahed AAA, Khalifa SAM, Elashal MH, Musharraf SG, Saeed A, Khatib A, Tahir HE, Zou X, Naggar YA, Mehmood A, et al. Cosmetic Applications of Bee Venom. Toxins. 2021; 13(11):810. https://doi.org/10.3390/toxins13110810

Chicago/Turabian Style

El-Wahed, Aida A. Abd, Shaden A. M. Khalifa, Mohamed H. Elashal, Syed G. Musharraf, Aamer Saeed, Alfi Khatib, Haroon Elrasheid Tahir, Xiaobo Zou, Yahya Al Naggar, Arshad Mehmood, and et al. 2021. "Cosmetic Applications of Bee Venom" Toxins 13, no. 11: 810. https://doi.org/10.3390/toxins13110810

APA Style

El-Wahed, A. A. A., Khalifa, S. A. M., Elashal, M. H., Musharraf, S. G., Saeed, A., Khatib, A., Tahir, H. E., Zou, X., Naggar, Y. A., Mehmood, A., Wang, K., & El-Seedi, H. R. (2021). Cosmetic Applications of Bee Venom. Toxins, 13(11), 810. https://doi.org/10.3390/toxins13110810

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