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Detoxification of Mycotoxins through Biotransformation

1
Department of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing 100193, China
2
Department of Applied Chemistry, College of Sciences, China Agricultural University, Beijing 100193, China
3
Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Beijing 100193, China
*
Author to whom correspondence should be addressed.
Toxins 2020, 12(2), 121; https://doi.org/10.3390/toxins12020121 (registering DOI)
Received: 30 December 2019 / Revised: 8 February 2020 / Accepted: 12 February 2020 / Published: 14 February 2020
(This article belongs to the Section Mycotoxins)
Mycotoxins are toxic fungal secondary metabolites that pose a major threat to the safety of food and feed. Mycotoxins are usually converted into less toxic or non-toxic metabolites through biotransformation that are often made by living organisms as well as the isolated enzymes. The conversions mainly include hydroxylation, oxidation, hydrogenation, de-epoxidation, methylation, glycosylation and glucuronidation, esterification, hydrolysis, sulfation, demethylation and deamination. Biotransformations of some notorious mycotoxins such as alfatoxins, alternariol, citrinin, fomannoxin, ochratoxins, patulin, trichothecenes and zearalenone analogues are reviewed in detail. The recent development and applications of mycotoxins detoxification through biotransformation are also discussed. View Full-Text
Keywords: fungi; mycotoxins; phytotoxins; detoxification; biotransformation; living organisms; enzymes; food safety and feed safety fungi; mycotoxins; phytotoxins; detoxification; biotransformation; living organisms; enzymes; food safety and feed safety
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Li, P.; Su, R.; Yin, R.; Lai, D.; Wang, M.; Liu, Y.; Zhou, L. Detoxification of Mycotoxins through Biotransformation. Toxins 2020, 12, 121.

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