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Toxins
Volume 11
Issue 12
10.3390/toxins11120728
Review Report
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Review
Peer-Review Record

The Therapeutic Effects and Pathophysiology of Botulinum Toxin A on Voiding Dysfunction Due to Urethral Sphincter Dysfunction

Toxins 2019, 11(12), 728; https://doi.org/10.3390/toxins11120728
by Yao-Lin Kao 1, Kuan-Hsun Huang 2, Hann-Chorng Kuo 3 and Yin-Chien Ou 1,4,*
Reviewer 1: Anonymous
Reviewer 2: Anonymous
Toxins 2019, 11(12), 728; https://doi.org/10.3390/toxins11120728
Submission received: 23 November 2019 / Revised: 10 December 2019 / Accepted: 11 December 2019 / Published: 13 December 2019
(This article belongs to the Special Issue Botulinum Toxin Treatment for Pain and Inflammation in Functional Urological Disorders)

Round 1

Reviewer 1 Report

This review articles mainly contains the effects of Botulinum toxin type A on various voiding dysfunction due to USD including cons and pros.

Still, this procedure has not generally approved, even though injection to the neurogenic detrusor overactivity has been approved. This article represents well current status of the clinical trials of Botulinum toxin type A on various voiding dysfunction due to USD.

Author Response

Please see the attachment

Author Response File: Author Response.docx

Reviewer 2 Report

The authors reviewed the literature about the therapeutic effects and pathophysiology of BoNT-A on voiding dysfunction due to urethral sphincter dysfunction.

This manuscript is interesting and new, nevertheless, this paper need some necessary corrections before publishing.

 

Keywords

Please include also “urethral sphincter dysfunction.

Introduction

 

Line 39: please add references at the end of the sentence: ..”has been reported; ”

Line 41: please add references at the end of the sentence.

Line 45: please add references at the end of the sentence.

Line 51: please add references at the end of the sentence: “.. two most widely used agents”

Line 77: please add references at the end of the sentence ..(TM).

 

Table 1.

Please add to abbreviations: Nil; IIQ-7 and UDI-6.

 

Line 159: please add the year of the publication: Hinmann and Baumann (…?).

Please say in manuscript: Table 1; Table 2; Table 3.

 

Table 2.

Please add to abbreviations: Nil; Pdet.

 

Line 236: please add references at the end of the sentence: “.. needle EMG”..

Line 245: please add references at the end of the sentence.

Line 249: please add the year of the publication: Liao and Kuo (…?).

Line 251: please add references at the end of the sentence.

 

Table .

Please add to abbreviations: Nil.

 

Line 295: please add references at the end of the sentence.

 

Author Response

Please see the attachment

Author Response File: Author Response.docx

Round 2

Reviewer 2 Report

This manuscript was suffizient corrected and improved.  

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