Hadrurid Scorpion Toxins: Evolutionary Conservation and Selective Pressures
Abstract
:1. Introduction
2. Results
2.1. Hadrurid Phylogenomic Tree and Divergence Time Estimate
2.2. The Repertoire of Venom-Specific Transcripts in the H. concolorous and H. aztecus Libraries
2.3. Molecular Evolution of Scorpine-Like Peptides (SLP)
3. Discussion
4. Conclusions
5. Materials and Methods
5.1. Specimen Collection and RNA Sequencing
5.2. Orthology Inference and Phylogenetic Methods
5.3. Venom Transcriptome Analyses of Hadrurus Concolorous and Hoffmannihadrurus Aztecus
5.4. Gene Tree Analysis and Molecular Evolution of Scorpines
Supplementary Materials
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Santibáñez-López, C.E.; Graham, M.R.; Sharma, P.P.; Ortiz, E.; Possani, L.D. Hadrurid Scorpion Toxins: Evolutionary Conservation and Selective Pressures. Toxins 2019, 11, 637. https://doi.org/10.3390/toxins11110637
Santibáñez-López CE, Graham MR, Sharma PP, Ortiz E, Possani LD. Hadrurid Scorpion Toxins: Evolutionary Conservation and Selective Pressures. Toxins. 2019; 11(11):637. https://doi.org/10.3390/toxins11110637
Chicago/Turabian StyleSantibáñez-López, Carlos E., Matthew R. Graham, Prashant P. Sharma, Ernesto Ortiz, and Lourival D. Possani. 2019. "Hadrurid Scorpion Toxins: Evolutionary Conservation and Selective Pressures" Toxins 11, no. 11: 637. https://doi.org/10.3390/toxins11110637