Next Article in Journal
Clostridium perfringens Iota-Toxin: Structure and Function
Next Article in Special Issue
Mycotoxin Contamination of Beverages: Occurrence of Patulin in Apple Juice and Ochratoxin A in Coffee, Beer and Wine and Their Control Methods
Previous Article in Journal / Special Issue
Preparation of an In-House Reference Material Containing Fumonisins in Thai Rice and Matrix Extension of the Analytical Method for Japanese Rice
Article Menu

Export Article

Open AccessReview
Toxins 2009, 1(2), 196-207;

Fluorescence Polarization Immunoassay of Mycotoxins: A Review

Bacterial Foodborne Pathogens and Mycology Research Unit, US Department of Agriculture, Agricultural Research Service, 1815 N. University St., Peoria, IL 61604, USA
Received: 17 November 2009 / Revised: 4 December 2009 / Accepted: 9 December 2009 / Published: 10 December 2009
(This article belongs to the Special Issue Advances in Mycotoxin Research)
Full-Text   |   PDF [309 KB, uploaded 11 December 2009]   |  


Immunoassays are routinely used in the screening of commodities and foods for fungal toxins (mycotoxins). Demands to increase speed and lower costs have lead to continued improvements in such assays. Because many reported mycotoxins are low molecular weight (below 1 kDa), immunoassays for their detection have generally been constructed in competitive heterogeneous formats. An exception is fluorescence polarization immunoassay (FPIA), a homogeneous format that does not require the separation of bound and free labels (tracer). The potential for rapid, solution phase, immunoassays has been realized in the development of FPIA for many of the major groups of mycotoxins, including aflatoxins, fumonisins, group B trichothecenes (primarily deoxynivalenol), ochratoxin A, and zearalenone. This review describes the basic principles of FPIA and summarizes recent research in this area with regard to mycotoxins. View Full-Text
Keywords: fluorescence polarization immunoassay; mycotoxins; review fluorescence polarization immunoassay; mycotoxins; review

Graphical abstract

This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Share & Cite This Article

MDPI and ACS Style

Maragos, C. Fluorescence Polarization Immunoassay of Mycotoxins: A Review. Toxins 2009, 1, 196-207.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Toxins EISSN 2072-6651 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top